The Influence of Hepatitis C Virus Infection on ORAL Health-Related Quality of Life in Patients with Oral Lichen Planus
| Autor: | Sorana D. Bolboacă, Andrea Maria Chisnoiu, Andreea Kui, Doina Iulia Rotaru, Radu Marcel Chisnoiu |
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| Rok vydání: | 2021 |
| Předmět: |
hepatitis C virus
medicine.medical_specialty Health Toxicology and Mutagenesis Hepatitis C virus Mucocutaneous zone Disease Hepacivirus Oral health medicine.disease_cause Article Global population oral lichen planus quality of life (QoL) Quality of life stomatognathic system Surveys and Questionnaires OHIP-14 questionnaire Medicine Humans In patient business.industry Public Health Environmental and Occupational Health medicine.disease Dermatology Hepatitis C humanities stomatognathic diseases Quality of Life Oral lichen planus business Lichen Planus Oral |
| Zdroj: | International Journal of Environmental Research and Public Health Volume 18 Issue 17 International Journal of Environmental Research and Public Health, Vol 18, Iss 9382, p 9382 (2021) |
| ISSN: | 1660-4601 |
| Popis: | Background: oral lichen planus (OLP) is a mucocutaneous disease that affects about 4% of the global population. Hepatitis C virus (HCV) was linked to lichen planus. The current study aimed to assess the impact of OLP associated or not with HCV infection on the oral health-related quality of life (OHRQoL). Methods: The study included patients diagnosed with OLP who filled in the Romanian version of OHIP-14 questionnaire at their first appointment and 6 months later, after the OLP treatment. A control group of OLP-free subjects similar as age and sex was also included in the study. Results: 68 patients with OLP and 46 controls were included in the study. The OHIP scores are significantly higher on OLP group than controls (p-value < 0.0001) and significantly reduced at 6-month follow-up (p-values: < 0.0001 pre- vs. post-treatment in OLP group). Patients with and without HCV associated with OLP demonstrated a similar oral quality of life (p-values > 0.05). Conclusions: the OHRQoL for patients suffering from OLP is compromised but is improved after treatment. The HCV associated with OLP did not influence the overall OHRQoL, but the patients who associate HCV reported more frequently aching in the mouth and discomfort eating food at six-month follow-up. |
| Databáze: | OpenAIRE |
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