WHAT IS THE IMPACT OF TEGASEROD ON GALLBLADDER EMPTYING?

Autor: Angeli Dogra, Johnson L. Thistle, Peter Rueegg, Victor Shi, James Novick, David L. Earnest, Don Luo, Robert S. Fisher, William D. Chey, Patrick O'Kane, Anthony Lembo
Rok vydání: 2003
Předmět:
Zdroj: American Journal of Gastroenterology. 98:S270-S271
ISSN: 0002-9270
DOI: 10.1111/j.1572-0241.2003.08552.x
Popis: Purpose: Tegaserod (T), a 5-HT4 receptor partial agonist that increases peristaltic activity of intestinal muscle, is used to treat irritable bowel syndrome with constipation (IBS-C). Whether T effects biliary tract motility is not known. The goal of this study was to evaluate the effects of T on gallbladder (GB) emptying and sphincter of Oddi (SO) function in female healthy volunteers (HV) and in female patients with IBS-C.
Databáze: OpenAIRE