WHAT IS THE IMPACT OF TEGASEROD ON GALLBLADDER EMPTYING?
Autor: | Angeli Dogra, Johnson L. Thistle, Peter Rueegg, Victor Shi, James Novick, David L. Earnest, Don Luo, Robert S. Fisher, William D. Chey, Patrick O'Kane, Anthony Lembo |
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Rok vydání: | 2003 |
Předmět: |
medicine.medical_specialty
Constipation Tegaserod Hepatology business.industry Gallbladder Gastroenterology medicine.disease Partial agonist medicine.anatomical_structure Internal medicine Sphincter of Oddi Medicine medicine.symptom Gallbladder Emptying business Irritable bowel syndrome Peristalsis medicine.drug |
Zdroj: | American Journal of Gastroenterology. 98:S270-S271 |
ISSN: | 0002-9270 |
DOI: | 10.1111/j.1572-0241.2003.08552.x |
Popis: | Purpose: Tegaserod (T), a 5-HT4 receptor partial agonist that increases peristaltic activity of intestinal muscle, is used to treat irritable bowel syndrome with constipation (IBS-C). Whether T effects biliary tract motility is not known. The goal of this study was to evaluate the effects of T on gallbladder (GB) emptying and sphincter of Oddi (SO) function in female healthy volunteers (HV) and in female patients with IBS-C. |
Databáze: | OpenAIRE |
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