Natural Transmission Model for Severe Fever With Thrombocytopenia Syndrome Bunyavirus in Villages of Hubei Province, China
| Autor: | Xuesen Xing, Xuhua Guan, Li Liu, Jianbo Zhan, Hongbo Jiang, Guoming Li, Jinfeng Xiong, Liangfei Tan, Junqiang Xu, Yongzhong Jiang, Xuan Yao, Faxian Zhan, Shaofa Nie |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Phlebovirus 0301 basic medicine China Veterinary medicine Disease reservoir 030231 tropical medicine Prevalence Observational Study Tick Antibodies Viral Bunyaviridae Infections Models Biological 03 medical and health sciences Ticks 0302 clinical medicine Blood serum Risk Factors Animals Humans Medicine Seroprevalence Disease Reservoirs biology business.industry Goats General Medicine Middle Aged biology.organism_classification medicine.disease Severe fever with thrombocytopenia syndrome Cross-Sectional Studies 030104 developmental biology RNA Viral Arachnid Vectors Cattle Female Haemaphysalis longicornis business Research Article |
| Zdroj: | Medicine |
| ISSN: | 0025-7974 |
| DOI: | 10.1097/md.0000000000002533 |
| Popis: | Severe fever with thrombocytopenia syndrome (SFTS), an emerging high-fatality infectious disease, is caused by a novel bunyavirus. However, a clear natural transmission model has not yet been established. We conducted a cross-sectional study with in-depth investigation of villages to systematically understand the transmission and risk factors among humans, host animals, and vectors. Village residents were interviewed using standardized questionnaires, in which there were confirmed cases of new infections, between August 2012 and May 2013. Serum samples from all villagers and animals, as well as tick specimens, were collected for qRT-PCR and antibody testing. The seropositivity rate among villagers was 8.4% (35/419), which was lower than that among domesticated animals (54.0%, 27/50; χ2 = 81.1, P |
| Databáze: | OpenAIRE |
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