Dwell time verification in brachytherapy based on time resolved in vivo dosimetry
| Autor: | J.G. Johansen, G. Kertzscher, E.B. Jørgensen, S. Rylander, L. Bentzen, S.B. Hokland, C.S. Søndergaard, A.K.M. With, S. Buus, K. Tanderup |
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| Rok vydání: | 2018 |
| Předmět: |
HDR brachytherapy
Male Materials science Time Factors medicine.medical_treatment Brachytherapy Biophysics General Physics and Astronomy Treatment verification In Vivo Dosimetry 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine In vivo dosimetry medicine Humans Radiology Nuclear Medicine and imaging Prostate cancer Point detector Dwell times Prostatic Neoplasms General Medicine Dwell time 030220 oncology & carcinogenesis Dose rate human activities Biomedical engineering |
| Zdroj: | Johansen, J G, Kertzscher, G, Jørgensen, E B, Rylander, S, Bentzen, L, Hokland, S B, Søndergaard, C S, With, A K M, Buus, S & Tanderup, K 2019, ' Dwell time verification in brachytherapy based on time resolved in vivo dosimetry ', Physica Medica, vol. 60, no. April, pp. 156-161 . https://doi.org/10.1016/j.ejmp.2019.03.031 |
| ISSN: | 1724-191X |
| Popis: | Purpose: This paper presents a method to verify dwell times during High Dose Rate (HDR) Brachytherapy (BT) by means of in vivo dosimetry (IVD), and reports on an afterloader's stability in dwell time control. Methods: In vivo dosimetry was performed during 20 HDR prostate cancer treatments using a point detector based on a radio-luminescence crystal (Al 2 O 3 :C) coupled to a fiber-optic cable. The dose rate was recorded at either 10 Hz or 20 Hz during the treatments. The “time of transit” when the source moved between two dwell positions was identified using the difference in count rate between two measurements. The dwell times were then determined by subtracting two adjacent times of transit. The measured dwell times were matched with the planned dwell times and categorised into two groups: Dwell times matching a single dwell position (identified) and dwell times matching the sum of multiple dwell positions (unidentified). Deviations between measured and planned dwell times were calculated for the identified dwell positions. Results: A total of 3518 dwell positions were analysed. The amount of identified dwell positions were 82%, which increased to 89% if the short dwell times ( |
| Databáze: | OpenAIRE |
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