Novel nucleotide triphosphates as potent P2Y2 agonists

Autor:	Stephen Robert Mack, Joanne Wynn, Richard J. Davenport, Raymond J. Owens, Frances C.A. Galvin, Jeremy Martin Davis, Verity Margaret Sabin, Daniel Christopher Brookings, Steve Lloyd
Jazyk:	angličtina
Rok vydání:	2016
Předmět:	Agonist Purinergic P2 Receptor Agonists DNA Complementary Magnetic Resonance Spectroscopy Stereochemistry medicine.drug_class Clinical Biochemistry Pharmaceutical Science Uridine Triphosphate Biochemistry Chemical synthesis Receptors Purinergic P2Y2 Structure-Activity Relationship Cell Line Tumor Drug Discovery medicine Humans Nucleotide Receptor Molecular Biology chemistry.chemical_classification Chemistry Nucleotides Reverse Transcriptase Polymerase Chain Reaction Organic Chemistry In vitro Nucleoside-diphosphate kinase Molecular Medicine Indicators and Reagents Nucleoside
Popis:	The synthesis and P2Y2 activities of a novel series of nucleoside triphosphates are described. Many of these compounds were potent agonists of the P2Y2 receptor.
Databáze:	OpenAIRE
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