Adenosine Triphosphate in the Adrenal Medulla of the Cow

Autor: B Hogberg, B Nilson, Nils-Åke Hillarp
Rok vydání: 1955
Předmět:
Zdroj: Nature. 176:1032-1033
ISSN: 1476-4687
0028-0836
DOI: 10.1038/1761032a0
Popis: DURING investigations on the specific adrenal medullary granules containing adrenaline and nor-adrenaline1, it was found that these structures have high contents of acid-labile phosphorus. In preliminary experiments with ion-exchange chromatography on ‘Dowex 2’ using formic and hydrochloric acid as eluting agents, a fraction was obtained in which the main part of the acid-labile phosphorus was recovered. Judging from the ultra-violet absorption and the ratio pentose: acid-labile phosphorus : total phosphorus, the chief compound in this fraction seemed to be adenosine triphosphate. Therefore the method of Cohn and Carter2 for separation of adenosine phosphates was applied to adrenal medullary extracts.
Databáze: OpenAIRE