Adenosine Triphosphate in the Adrenal Medulla of the Cow
Autor: | B Hogberg, B Nilson, Nils-Åke Hillarp |
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Rok vydání: | 1955 |
Předmět: |
chemistry.chemical_classification
Multidisciplinary Chromatography Phosphorus chemistry.chemical_element Pentose Hydrochloric acid Fraction (chemistry) Adenosine Phosphates chemistry.chemical_compound Adenosine Triphosphate medicine.anatomical_structure chemistry Adrenal Medulla medicine Animals Cattle Female Total phosphorus Adrenal medulla Adenosine triphosphate |
Zdroj: | Nature. 176:1032-1033 |
ISSN: | 1476-4687 0028-0836 |
DOI: | 10.1038/1761032a0 |
Popis: | DURING investigations on the specific adrenal medullary granules containing adrenaline and nor-adrenaline1, it was found that these structures have high contents of acid-labile phosphorus. In preliminary experiments with ion-exchange chromatography on ‘Dowex 2’ using formic and hydrochloric acid as eluting agents, a fraction was obtained in which the main part of the acid-labile phosphorus was recovered. Judging from the ultra-violet absorption and the ratio pentose: acid-labile phosphorus : total phosphorus, the chief compound in this fraction seemed to be adenosine triphosphate. Therefore the method of Cohn and Carter2 for separation of adenosine phosphates was applied to adrenal medullary extracts. |
Databáze: | OpenAIRE |
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