Survival and Control Prognosticators of Recurrent Gynecological Malignancies of the Pelvis and Para-aortic Region Treated with Stereotactic Body Radiation Therapy
| Autor: | A. Ricco, John Lamond, Jun Yang, Alexandra L. Hanlon, Joel Noumoff, Kaylette Jenkins, Shaakir Hasan, Michael Good, Luther W. Brady, Jing Feng, Rachelle Lanciano |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Cancer Research medicine.medical_specialty endometrial neoplasms Stereotactic body radiation therapy Urology Improved survival stereotactic body radiation therapy lcsh:RC254-282 03 medical and health sciences 0302 clinical medicine uterine cervical neoplasms Carcinosarcoma medicine Uterine Neoplasm Pelvis Original Research SBRT Performance status business.industry ovarian neoplasms medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Surgery Serous fluid 030104 developmental biology medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis business gynecological malignancies uterine neoplasms Median survival |
| Zdroj: | Frontiers in Oncology Frontiers in Oncology, Vol 6 (2016) |
| ISSN: | 2234-943X |
| Popis: | Purpose: To define prognostic factors associated with improved survival and local control for gynecologic cancer recurrences limited to the pelvis and para-aortic region using stereotactic body radiation therapy (SBRT). Methods: Between 2/2008 and 7/2014, 30 women (35 targets) with pelvic or PA recurrence of endometrioid (n=12), cervical (n=11), ovarian (n=3), uterine serous (n=2) or carcinosarcoma (n=2) CA were treated with SBRT. Eleven recurrences were located in the central pelvis(CP), 11 along the pelvic sidewall(PSW), and 13 in the para-aortic (PA)region. Results: Five-year survival for all patients was 42% with a median survival of 43.4 months. Multivariate analysis revealed better performance status (PS) and smaller clincial tumor volume (CTV) were significant for improved survival (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|