Structure, antioxidant property and protection on PC12 of a polysaccharide isolated and screened from Abelmoschus esculentus L.Moench (okra)
| Autor: | Xiao-Ling Zhang, Zhen-Yuan Zhu, Xue-Qing Geng, Li-Chao Pan, Hui-Qing Sun, Jia-He Wang, Wei Jiang, Chun-Yu Liu, Yang-Yang Sun |
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| Rok vydání: | 2021 |
| Předmět: |
Arabinose
Antioxidant Rhamnose medicine.medical_treatment Plant Science Polysaccharide 01 natural sciences Biochemistry Analytical Chemistry chemistry.chemical_compound medicine Food science chemistry.chemical_classification biology 010405 organic chemistry Organic Chemistry Protein primary structure food and beverages biology.organism_classification 0104 chemical sciences carbohydrates (lipids) 010404 medicinal & biomolecular chemistry Point of delivery chemistry Galactose lipids (amino acids peptides and proteins) Abelmoschus |
| Zdroj: | Natural Product Research. 36:1441-1447 |
| ISSN: | 1478-6427 1478-6419 |
| DOI: | 10.1080/14786419.2021.1887867 |
| Popis: | AeP-P-2, a pectic polysaccharide, was extracted from the fruit pod of okra. It composed of rhamnose (Rha), arabinose (Ara), glucose (Glc), galactose (Gal) and galacturonic acid (GalA) with the ratio of 4.75:2.01:1.00:4.91:7.24. The main structural feature of AeP-P-2 are 1,4-linked galacturonan units (homogalacturonan backbone) and (1 → 2) and (1 → 2,4) linked Rha (rhamnogalacturonan I region). And the other side chains contained →1)-linked Ara, (1 → 5)-linked Ara, (1 → 4)-linked Glc, (1 → 6)-linked Gal, (1 → 4)-linked Rha, (1 → 2,4)-linked Rha, →1)-linked Ara and →1)-linked Gal. When the concentration of AeP-P-2 was 3.2 mg/mL, the scavenging rates on DPPH·, ABTS, O2−· and ·OH reached to 61.88%, 87.10%, 52.17% and 60.32%, respectively. AeP-P-2 also could protect PC12 cells from the damage of H2O2 and reduce apoptosis caused by oxidative damage by decreasing the level of ROS. The findings indicated that okra was a functional vegetable and AeP-P-2 was worth studying and developing into antioxidant component. |
| Databáze: | OpenAIRE |
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