Reinfusion of aspirated pericardial blood during CPB. Part I. Hypothesis: laparotomy sponges are a significant part of the CPB circuit?
| Autor: | Brian S. Bull, Karen L. Hay |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Surgical Sponges
medicine.medical_specialty medicine.medical_treatment Blood Loss Surgical law.invention Blood Transfusion Autologous law Laparotomy medicine Cardiopulmonary bypass Coagulopathy Humans Molecular Biology Oxygenator Cardiopulmonary Bypass business.industry Significant part Cell Biology Hematology Heparin Biocompatible material medicine.disease Surgery surgical procedures operative Pericardial sac Anesthesia Molecular Medicine business medicine.drug |
| Zdroj: | Blood cells, moleculesdiseases. 34(2) |
| ISSN: | 1079-9796 |
| Popis: | Blood accumulating in the pericardial sac is routinely reinfused during cardiopulmonary bypass (CPB) surgery. Such reinfusion has been associated with an increased incidence of serious complications such as coagulopathy, systemic inflammation, and neurologic sequelae. We hypothesize that some of these complications occur because the reinfused blood has been exposed to and activated by laparotomy sponges used to elevate the heart during vein graft emplacement. Such laparotomy sponges expose accumulating pericardial blood to a large, raw, cotton surface with an area approximately five times that of the CPB circuit (excluding the biocompatible oxygenator membrane). Because the reinfused blood has been exposed to this surface, the sponge becomes, in essence, a significant—though inapparent—part of the CPB circuit. Steps should be taken to either eliminate the sponge or to reduce the area of this foreign surface and make it more biocompatible. |
| Databáze: | OpenAIRE |
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