Different influence of incongruent follicular development on in vitro fertilization-embryo transfer and gamete intrafallopian transfer pregnancy rates
| Autor: | Philip Jm Lowe, David L. Healy, Luk Rombauts, Talia Eldar-Geva, Vivien MacLachlan |
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| Rok vydání: | 1998 |
| Předmět: |
Infertility
Adult medicine.medical_specialty Pregnancy Rate medicine.medical_treatment education Controlled ovarian hyperstimulation Fertilization in Vitro Biology Ovarian Hyperstimulation Syndrome Ovarian Follicle Pregnancy Follicular phase medicine Humans Gamete intrafallopian transfer Retrospective Studies Gynecology In vitro fertilisation Obstetrics and Gynecology medicine.disease Embryo Transfer humanities Embryo transfer Gamete Intrafallopian Transfer Pregnancy rate Logistic Models Reproductive Medicine Regression Analysis Female Infertility Female |
| Zdroj: | Fertility and sterility. 70(6) |
| ISSN: | 0015-0282 |
| Popis: | Objective: To compare the influence of incongruent (asymmetric) follicular development on treatment outcome in IVF-ET and GIFT cycles. Design: A retrospective comparative study. Setting: Tertiary referral center for infertility. Patient(s): Five hundred forty-three consecutive assisted reproduction cycles (428 IVF-ET and 115 GIFT) in 422 infertile patients. Intervention(s): Controlled ovarian hyperstimulation (COH) and IVF-ET or GIFT. Main Outcome Measure(s): The incongruity ratio as a parameter of the asymmetry in follicular development and pregnancy rate (PR). Result(s): For GIFT cycles, the PRs were 37.8% and 15.7% in cycles with congruent and incongruent follicular development, respectively. However, for IVF-ET cycles, the PR was not affected by incongruent follicular development: 28.2% and 29.0%, respectively. An inverse relationship was observed between the degree of incongruity and the estimated probability of pregnancy in GIFT cycles but not in IVF-ET cycles. Neither the side of the dominant ovary nor the degree of incongruity were consistent in consecutive cycles. Conclusion(s): Incongruent follicular development during COH has a significantly negative influence on the outcome of GIFT cycles but not on the outcome of IVF-ET cycles. The reason for this difference is not clear. We recommend considering IVF-ET instead of GIFT if incongruent follicular development occurs. |
| Databáze: | OpenAIRE |
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