Reduction in cardiovascular risk factors and insulin dose, but no beta-cell regeneration 1 year after Roux-en-Y gastric bypass in an obese patient with type 1 diabetes: A case report
| Autor: | Siv H. Jacobsen, Lisbeth E. Hvolris, Jens J. Holst, Sten Madsbad, Lars Naver, Nils B. Jørgensen, Kirstine N. Bojsen-Møller, Dorte Worm, Carsten Dirksen, D.L. Hansen |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
medicine.medical_specialty Endocrinology Diabetes and Metabolism Population Gastric Bypass Gastroenterology chemistry.chemical_compound High-density lipoprotein Risk Factors Insulin-Secreting Cells Internal medicine medicine Humans Insulin education Type 1 diabetes education.field_of_study Nutrition and Dietetics business.industry digestive oral and skin physiology nutritional and metabolic diseases Type 2 Diabetes Mellitus medicine.disease Glucagon-like peptide-1 Obesity Obesity Morbid Diabetes Mellitus Type 1 Endocrinology Blood pressure chemistry Cardiovascular Diseases Female business Body mass index |
| Zdroj: | Obesity Research & Clinical Practice. 7:e269-e274 |
| ISSN: | 1871-403X |
| DOI: | 10.1016/j.orcp.2012.01.002 |
| Popis: | Summary Experience with Roux-en-Y gastric bypass in patients with type 1 diabetes is very limited, despite an increasing prevalence of obesity also in this population. We describe changes in anthropometric measures, insulin dose, HbA1c, blood pressure, lipid status, and metabolic response to a liquid mixed meal throughout the first year after RYGB in an obese patient with type 1 diabetes. No change in HbA1c was observed, but a 48% reduction in weight-adjusted insulin dose and improvements in cardiovascular risk factors was seen 1 year after surgery. Exaggerated secretions of anorexigenic gut hormones were seen during the meals. |
| Databáze: | OpenAIRE |
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