Herpes zoster ophthalmicus and varicella zoster virus vasculopathy
| Autor: | Denise de Freitas, Guido Carlos Levi, Francisco Bandeira, Marina Roizenblatt, Rubens Belfort |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Herpesvirus 3 Human Herpes Zoster Vaccine viruses medicine.disease_cause Herpervirus humano 3 Acidente vascular cerebral 03 medical and health sciences 0302 clinical medicine lcsh:Ophthalmology Risk Factors Epidemiology medicine Humans Herpes zoster vaccine Vascular Diseases Risk factor Stroke Vascular disease business.industry Herpesvirus 3 human Varicella zoster virus Vacina contra herpes zoster virus diseases General Medicine medicine.disease Dermatology Surgery Ophthalmology Herpes Zoster Ophthalmicus Herpes zoster ophthalmicus lcsh:RE1-994 Herpes zoster oftálmico 030221 ophthalmology & optometry business Complication 030217 neurology & neurosurgery |
| Zdroj: | Arquivos Brasileiros de Oftalmologia, Vol 79, Iss 2, Pp 126-129 (2016) Arquivos Brasileiros de Oftalmologia v.79 n.2 2016 Arquivos brasileiros de oftalmologia Conselho Brasileiro de Oftalmologia (CBO) instacron:CBO Arquivos Brasileiros de Oftalmologia, Volume: 79, Issue: 2, Pages: 126-129, Published: APR 2016 |
| ISSN: | 1678-2925 |
| Popis: | Herpes zoster (HZ) corresponds to the reactivation of varicella zoster virus (VZV). Among adults, the ophthalmic division of the trigeminal nerve is one of the most common sites of involvement. Vasculopathy caused by HZ is associated with significant morbidity and mortality, affecting structures such as the brain, which can lead to stroke. In this review, we analyzed the epidemiological and clinical aspects of the vascular involvement of VZV, focusing on the peculiarities of its association with ocular HZ. A review of the available literature indicated that ocular involvement of HZ was a risk factor for vasculopathy after adjusting for age, sex, body mass index, smoking, indicators of metabolic syndrome, and vascular and heart diseases. Considering the severity of this complication, vascular disease mediated by VZV requires early diagnosis and aggressive treatment. Finally, the anti-HZ vaccine has been recommended as a prophylactic measure in the elderly, but it should be used with caution in immunocompromised individuals. RESUMO Herpes zoster (HZ) corresponde à reativação do vírus varicela zoster (VVZ) e, entre os adultos, o envolvimento da divisão oftálmica do nervo trigêmeo é um dos locais mais comuns A vasculopatia associada ao HZ é uma complicação dotada de grande morbimortalidade e afeta diferentes estruturas, favorecendo, inclusive o acidente vascular cerebral. Nesta revisão analisamos aspectos epidemiológicos e clínicos da vasculopatia mediada pelo VZV, bem como as peculiaridades relacionadas com o HZ ocular. De acordo com dados disponíveis na literatura, o acometimento ocular pelo HZ mostrou ser um fator de risco para vasculopatia após se ajustar para idade, sexo, índice de massa corporal, tabagismo, indicadores da síndrome metabólica, doença vascular e cardiopatias. Em face da gravidade dessa complicação, a doença vascular mediada pelo VZV requer diagnóstico precoce e tratamento agressivo. A vacina anti-HZ tem sido recomendada profilaticamente em idosos, mas deve ser usada com cautela em indivíduos imunocomprometidos. |
| Databáze: | OpenAIRE |
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