Demonstration of Antibodies to Mosquito Antigens in Man by Immunodiffusion and ELISA
| Autor: | Tapio Rantanen, Kirsi Ailus, Timo Reunala, Timo Palosuo, Markus Brummer-Korvenkontio |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Immunodiffusion
Allergy Immunology Adult population Enzyme-Linked Immunosorbent Assay Antibodies Antigen-Antibody Reactions Antigen Aedes parasitic diseases medicine Animals Humans Immunology and Allergy Mosquito cell biology General Medicine biology.organism_classification medicine.disease Virology Sting Culicidae biology.protein Antibody |
| Zdroj: | International Archives of Allergy and Immunology. 78:375-379 |
| ISSN: | 1423-0097 1018-2438 |
| DOI: | 10.1159/000233916 |
| Popis: | Cutaneous reactions to mosquito bites are believed to be immunologically mediated, but knowledge of the underlying mechanisms is very limited. In the present work, comprising 598 subjects, we show that precipitating and ELISA-reactive IgG-class antibodies occur frequently in the adult population. The operating antigen(s) were found in whole-body extracts of Aedes mosquitoes and also in a continuous mosquito cell line culture. The appearance of antimosquito antibodies seems to be correlated with the exposure to mosquito bites; however, massive exposure at an early age may result in a suppressed response. |
| Databáze: | OpenAIRE |
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