CMC stabilized nano silver synthesis, characterization and its antibacterial and synergistic effect with broad spectrum antibiotics
| Autor: | Grasian Immanuel, P. Prema, S. Thangapandiyan |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Silver
Polymers and Plastics Bacillus cereus Metal Nanoparticles Nanoparticle Nanotechnology Microbial Sensitivity Tests 02 engineering and technology Bacterial growth 010402 general chemistry 01 natural sciences Silver nanoparticle Materials Chemistry Fourier transform infrared spectroscopy biology Chemistry Organic Chemistry technology industry and agriculture Silver Nano Drug Synergism 021001 nanoscience & nanotechnology Antimicrobial biology.organism_classification Anti-Bacterial Agents 0104 chemical sciences 0210 nano-technology Antibacterial activity Nuclear chemistry |
| Zdroj: | Carbohydrate Polymers. 158:141-148 |
| ISSN: | 0144-8617 |
| DOI: | 10.1016/j.carbpol.2016.11.083 |
| Popis: | In the present study silver nanoparticles were synthesized by reduction of AgNO3 using aqueous CMC solution, which acts as both reducing and capping agent. The formation of AgNO3 nanoparticles was observed visually by color change and these nanoparticles were characterized through UV-vis spectroscopy, FTIR, XRD, SEM, EDS and AFM. The FTIR peaks observed to be ranging from 3300 to 605cm-1. The AFM image clearly showed the surface morphology of well dispersed nanoparticles. SEM image illustrates the nanoparticles with spherical shape. The crystalline nature of the particles was assured by XRD analysis. The antimicrobial activity of nanoparticles was tested against human bacterial pathogens (Bacillus cereus, Staphylococcus aureus, S. epidermidis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhimurium &Vibrio vulnificus). The bacterial growth was highly inhibited by the nanoparticles. The synergistic effect of nanoparticles in combination with selected broad spectrum antibiotics against the tested bacteria determined strong growth inhibitory activity. |
| Databáze: | OpenAIRE |
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