Similar Performance of Trabectome and Ahmed Glaucoma Devices in a Propensity Score-matched Comparison
| Autor: | Kevin Kaplowitz, Eric N. Brown, Tarek A. Shazly, Sushma Kola, Susannah Waxman, Hamed Esfandiari, Nils A. Loewen |
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| Rok vydání: | 2018 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty Intraocular pressure genetic structures medicine.medical_treatment Glaucoma Trabeculectomy Prosthesis Implantation Tonometry Ocular 03 medical and health sciences 0302 clinical medicine Trabecular Meshwork Ophthalmology medicine Humans Trabectome Glaucoma Drainage Implants Propensity Score Intraocular Pressure Aged Retrospective Studies Phacoemulsification business.industry Middle Aged medicine.disease eye diseases Treatment Outcome 030104 developmental biology Baseline characteristics Propensity score matching 030221 ophthalmology & optometry Visual Field Tests Female sense organs Visual field loss Visual Fields business |
| Zdroj: | Journal of Glaucoma. 27:490-495 |
| ISSN: | 1057-0829 |
| DOI: | 10.1097/ijg.0000000000000960 |
| Popis: | Purpose: To apply propensity score matching to Ahmed glaucoma drainage implants (AGI) to trabectome-mediated ab interno trabeculectomy (AIT). Recent data suggest that AIT can produce results similar to AGI traditionally reserved for more severe glaucoma. Methods: AGI and AIT patients with at least 1 year of follow-up were included. The primary outcome measures were intraocular pressure (IOP), glaucoma medications, and a Glaucoma Index (GI) score. GI reflected glaucoma severity based on visual field, the number of preoperative medications, and preoperative IOP. Score matching used a genetic algorithm consisting of age, sex, type of glaucoma, concurrent phacoemulsification, baseline number of medications, and baseline IOP. Patients without a close match were excluded. Results: Of 152 patients, 34 AIT patients were matched to 32 AGI patients. Baseline characteristics including ethnicity, IOP, the number of medications, glaucoma type, the degree of visual field loss and GI were not significantly different between AIT and AGI. AIT had a preoperative IOP of 23.6±8.1 mm Hg compared with 26.5+10.6 mm Hg for AGI. At 12 months, the mean IOP was 15.0±9 mm Hg for AIT versus 15.0±4 mm Hg for AGI (P=0.8), whereas the number of drops was 2.3±2.2 for AIT versus 3.6±1.3 for AGI (P=0.016). Only 6 AIT patients (17.6%) required further surgery within the first 12 months versus 9 (28%) for AGI. Success, defined as IOP |
| Databáze: | OpenAIRE |
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