Correction of endothelial dysfunction with impaza preparation in complex with enalapril and losartan during modeling of NO deficiency

Autor:	E. B. Artyushkova, T. G. Pokrovskaya, M. V. Pokrovskii, E. N. Pashin, A. S. Belous, E. S. Zhavbert, V. I. Kochkarov
Rok vydání:	2010
Předmět:	Male medicine.medical_specialty Endothelium Nitric Oxide General Biochemistry Genetics and Molecular Biology Antibodies Losartan Nitric oxide chemistry.chemical_compound Enalapril Internal medicine medicine Animals Endothelial dysfunction Rats Wistar business.industry General Medicine medicine.disease Rats Endocrinology medicine.anatomical_structure NG-Nitroarginine Methyl Ester chemistry Hypertension business hormones hormone substitutes and hormone antagonists circulatory and respiratory physiology medicine.drug
Zdroj:	Bulletin of experimental biology and medicine. 148(3)
ISSN:	1573-8221
Popis:	Modeling of NO deficiency by administration of L-NAME to rats led to the development of arterial hypertension and endothelial dysfunction. Pronounced endothelium and cardioprotective effects of impaza under these experimental conditions manifested more markedly during combined administration of the preparation with standard hypotensive preparations enalapril and losartan.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4eca5b933f3bf9ab0ff9f5dacf217c5 https://pubmed.ncbi.nlm.nih.gov/20396726 Zobrazit plný text záznamu Full text from SpringerLink