| Autor: |
Lucas de Figueiredo Soveral, Paola Aparecida de Almeida, Yasmin Kreutz, Vitoria Agnoletto Ribeiro, Rafael Frandoloso, Luiz Carlos Kreutz |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Fish and Shellfish Immunology Reports, Vol 3, Iss, Pp 100053-(2022) |
| ISSN: |
2667-0119 |
| Popis: |
The early immune-related events arising from the interaction of antigen and innate immune cells are central to modulating the acquired immune response. Ideally, the immunizing antigen should elicit immunological changes similar to that observed after infection with the wild type pathogen. Here, we evaluated early changes on the expression of selected proinflammatory genes (TNF-α, IL-1β, IRAK4 and myeloperoxidase) and innate immune parameters (serum myeloperoxidase, lysozyme and complement hemolytic activity) in silver catfish vaccinated or infected with Aeromonas hydrophila, the etiological agent of hemorrhagic septicemia. The humoral immune response and resistance to challenge were also evaluated in vaccinated and placebo inoculated fish. We found that the expression of TNF-α and IL-1β genes was higher (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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