Older Donation After Circulatory Death Kidneys for Older Recipients: A Single-Center Experience
| Autor: | Argiris Asderakis, Usman Khalid, Muhammad Jameel, Laszlo Szabo, Tarique Sabah, R. Chavez, M. A. Ilham, Elijah Ablorsu |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Tissue and Organ Procurement Renal function Single Center Median follow-up medicine Humans Kidney transplantation Aged Transplantation business.industry Graft Survival Age Factors Transplant Waiting List Middle Aged medicine.disease Kidney Transplantation Circulatory death Tissue Donors Treatment Outcome Donation Female Surgery Graft survival business Glomerular Filtration Rate |
| Zdroj: | Transplantation Proceedings. 51:701-706 |
| ISSN: | 0041-1345 |
| DOI: | 10.1016/j.transproceed.2019.01.081 |
| Popis: | The number of older patients is increasing on the transplant waiting list. Donation after circulatory death (DCD) kidney transplantation has increased, but there remains hesitancy in use of older DCD organs. The aim of this study was to evaluate outcomes of directing older DCD donor kidneys into older recipients. Methods Patients 60 years or older who received transplants from DCD donors 60 years or older, between February 2010 and January 2014, were identified from a prospectively maintained database. Results Over a 4-year period, 88 patients 60 years or older received DCD kidney transplants from donors 60 years or older. Of these 44 (55%) were 60 to 69 years old and 40 (45%) were 70 years or older. Median follow up was 63 months. Patient survival was 95% and 79% at 1 and 5 years, respectively, with a survival in those 70 years and older (69%) compared with those aged 60 to 69 (88%) years (P = .01). Censored for death graft survival was 94% and 80% at 1 and 5 years, respectively. Median estimated glomerular filtration rate at 12 months and 36 months was 36 mL/min (range, 11–70 mL/min) and 39.5 mL/min (range, 11–77 mL/min), respectively. Conclusions Older DCD kidneys, when transplanted into older recipients, result in good patient and graft survival and an acceptable graft function, especially considering their age. This represents a good use of this organ resource. |
| Databáze: | OpenAIRE |
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