Clinical and lymphocyte responses to beta-carotene supplementation in 11 HIV-positive patients with chronic oral candidiasis
| Autor: | Sol Silverman, George E. Kaugars, William T. Riley, Richard B. Brandt, Daniel P. Stites, John Gallo, Joan S. Thompson |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Male medicine.medical_specialty Lymphocyte Human immunodeficiency virus (HIV) medicine.disease_cause Gastroenterology Pathology and Forensic Medicine chemistry.chemical_compound Immune system Candidiasis Oral beta-Carotene Internal medicine HIV Seropositivity medicine Humans Lymphocyte Count Lymphocytes General Dentistry Mycosis Analysis of Variance AIDS-Related Opportunistic Infections Triglyceride business.industry Middle Aged Chronic oral candidiasis beta Carotene medicine.disease Carotenoids Lipids CD4 Lymphocyte Count Treatment Outcome medicine.anatomical_structure chemistry Chronic Disease Immunology Female business CD8 |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology. 78:442-447 |
| ISSN: | 0030-4220 |
| Popis: | Eleven HIV-positive patients with chronic oral candidiasis were supplemented with 60 to 120 mg of beta-carotene daily for 3 to 7 months. Lymphocyte profiles were evaluated at intervals to help assess immune competence. Although there was a modest increase in some lymphocyte values at 2 months, there was a significant decrease in numbers of CD4 and CD8 cells and CD4 percentage of lymphocytes after 6 months of beta-carotene supplementation. Serum triglyceride and liver enzyme levels were not affected by the beta-carotene supplementation. No improvement was observed in the control of the oral candidiasis. Under the conditions of the study, there was no indication that daily beta-carotene supplements enhanced immune competence or was of benefit in managing oral candidiasis. |
| Databáze: | OpenAIRE |
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