A comparison of COVID-19 inpatients by HIV status
| Autor: | Sarah Flannery, Rehana Rasul, Joseph Mcgowan, Rebecca M. Schwartz, Bruce Hirsch, David Hirschwerk, Frances Wallach |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Population HIV Infections Dermatology Disease Chronic liver disease Azithromycin 03 medical and health sciences COVID-19 Testing 0302 clinical medicine Internal medicine Humans Medicine Pharmacology (medical) 030212 general & internal medicine education Inpatients 0303 health sciences education.field_of_study SARS-CoV-2 030306 microbiology business.industry Mortality rate Public Health Environmental and Occupational Health COVID-19 Hydroxychloroquine medicine.disease Infectious Diseases Coinfection Viral disease business medicine.drug |
| Zdroj: | International Journal of STD & AIDS. 32:1149-1156 |
| ISSN: | 1758-1052 0956-4624 |
| DOI: | 10.1177/09564624211023015 |
| Popis: | COVID-19 in-hospital morbidity and mortality in people living with HIV (PLWH) were compared to HIV-negative COVID-19 patients within a New York City metropolitan health system, the hardest hit region in the United States early in the pandemic. A total of 10,202 inpatients were diagnosed with COVID-19, of which 99 were PLWH. PLWH were younger (58.3 years (SD = 12.42) versus 64.32 years (SD = 16.77), p < 0.001) and had a higher prevalence of men (73.7% versus 57.9%, p = 0.002) and Blacks (43.4% versus 21.7%, p < 0.001) than the HIV-negative population. PLWH had a higher prevalence of malignancies (18% versus 7%, p = < 0.001), chronic liver disease (12% versus 3%, p < 0.001), and end-stage renal disease (11% versus 4%, p = 0.007). Use of a ventilator, admission to the ICU, and in-hospital mortality were not different. Of the 99 PLWH, 12 were virally unsuppressed and 9 had CD4% < 14. Two of the 12 virally unsuppressed patients and 4/9 patients with CD4% < 14 died. Ninety-one of the 99 PLWH were on treatment for HIV, and 5 of the 8 not on treatment died. Among PLWH with prior values, absolute CD4 count decreased an average of 192 cells/mm3 at the time of COVID-19 diagnosis ( p < 0.001). Hospitalized patients with HIV and COVID-19 coinfection did not have worse outcomes than the general population. Among PLWH, those with CD4% |
| Databáze: | OpenAIRE |
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