[18F]fluorodeoxyglucose uptake as a predictor of large joint destruction in patients with rheumatoid arthritis
| Autor: | Yukio Yonemoto, Yoshito Tsushima, Kenji Takagishi, Tetsuya Kaneko, Tsutomu Kobayashi, Chisa Okura, Kimihiko Takeuchi, Koichi Okamura |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male musculoskeletal diseases medicine.medical_specialty Hand Joints Prednisolone Radiography Immunology Standardized uptake value 030218 nuclear medicine & medical imaging Arthritis Rheumatoid 03 medical and health sciences 0302 clinical medicine Rheumatology Fluorodeoxyglucose F18 Foot Joints Internal medicine Humans Immunology and Allergy Medicine Radionuclide Imaging Aged Retrospective Studies 030203 arthritis & rheumatology Fluorodeoxyglucose Receiver operating characteristic business.industry Retrospective cohort study Middle Aged medicine.disease Methotrexate Antirheumatic Agents Rheumatoid arthritis Disease Progression Female business Nuclear medicine medicine.drug |
| Zdroj: | Rheumatology International. 36:109-115 |
| ISSN: | 1437-160X 0172-8172 |
| DOI: | 10.1007/s00296-015-3331-0 |
| Popis: | The present retrospective study investigated the relationship between [18F]fluorodeoxyglucose–positron emission tomography (FDG-PET) findings and subsequent progression of joint destruction on plain X-ray. Nineteen rheumatoid arthritis (RA) patients (59 joints) who underwent FDG-PET and whose joints could be evaluated on plain X-ray 5 years later were included in this retrospective investigation. The relationship between the standardized uptake value (SUV) on FDG-PET and Larsen grade progression on plain X-ray was investigated for each joint. Factors related to progression of joint destruction were also investigated. Joints with advanced joint destruction (Larsen grades IV and V) on X-ray imaging at the time of FDG-PET were excluded. On initial plain X-ray images taken at the time of FDG-PET, a significant correlation was observed between the initial SUV of each joint and the progression of joint destruction 5 years later (R = 0.47, P |
| Databáze: | OpenAIRE |
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