Lung Ultrasound Findings Associated With COVID-19 ARDS, ICU Admission, and All-Cause Mortality
| Autor: | Matias Greve Lindholm, Søren Helbo Skaarup, Reza Jabbari, Caroline Espersen, Tor Biering-Sørensen, Henning Bundgaard, Niklas Dyrby Johansen, Jørn Carlsen, Elke Platz, Ole Peter Kristiansen, Charlotte Suppli Ulrik, Ole Kirk, Alia Saed Alhakak, Christian Hassager, Anne Bjerg Nielsen, Klaus Nielsen Jeschke, Kristoffer Grundtvig Skaarup, Olav W. Nielsen, Pradeesh Sivapalan, Mats Christian Højbjerg Lassen, Gunnar Gislason, Jannie Nørgaard Lind, Morten Sengeløv, Jens-Ulrik Stæhr Jensen, Morten Schou, Kasper Iversen |
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| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty ARDS Lung ultrasound Coronavirus disease 2019 (COVID-19) business.industry Incidence (epidemiology) COVID-19 Risk stratifi-cation General Medicine Critical Care and Intensive Care Medicine medicine.disease Logistic regression Procalcitonin In-hospital outcomes Internal medicine Cohort Medicine Observational study business |
| Zdroj: | Espersen, C, Platz, E, Skaarup, K G, Lassen, M C H, Lind, J N, Johansen, N D, Sengeløv, M, Alhakak, A S, Nielsen, A B, Bundgaard, H, Hassager, C, Jabbari, R, Carlsen, J, Kirk, O, Lindholm, M G, Kristiansen, O P, Nielsen, O W, Jeschke, K N, Ulrik, C S, Sivapalan, P, Gislason, G, Iversen, K, Jensen, J U S, Schou, M, Skaarup, S H & Biering-Sørensen, T 2022, ' Lung Ultrasound Findings Associated With COVID-19 ARDS, ICU Admission, and All-Cause Mortality ', Respiratory Care, vol. 67, no. 1, pp. 66-75 . https://doi.org/10.4187/respcare.09108 |
| ISSN: | 1943-3654 |
| Popis: | BACKGROUND: As lung ultrasound (LUS) has emerged as a diagnostic tool in patients with COVID-19, we sought to investigate the association between LUS findings and the composite in-hospital outcome of ARDS incidence, ICU admission, and all-cause mortality. METHODS: In this prospective, multi-center, observational study, adults with laboratory-confirmed SARS-CoV-2 infection were enrolled from non-ICU in-patient units. Subjects underwent an LUS evaluating a total of 8 zones. Images were analyzed off-line, blinded to clinical variables and outcomes. A LUS score was developed to integrate LUS findings: ≥ 3 B-lines corresponded to a score of 1, confluent B-lines to a score of 2, and subpleural or lobar consolidation to a score of 3. The total LUS score ranged from 0–24 per subject. RESULTS: Among 215 enrolled subjects, 168 with LUS data and no cur-rent signs of ARDS or ICU admission (mean age 59 y, 56% male) were included. One hundred thirty-six (81%) subjects had pathologic LUS findings in ≥ 1 zone (≥ 3 B-lines, confluent B-lines, or consolidations). Markers of disease severity at baseline were higher in subjects with the composite outcome (n = 31, 18%), including higher median C-reactive protein (90 mg/L vs 55, P |
| Databáze: | OpenAIRE |
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