Efficacy in type 2 diabetes mellitus remission in patients undergoing bariatric surgery
| Autor: | Modesto Enrique Moneva Arce, José Enrique Palacio Abizanda, Bruno Francisco García Bray, María Araceli García Nuñez, José Pablo Suárez Llanos, José Gregorio Oliva García, Francisca Pereyra-García Castro |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Gastric bypass Bariatric Surgery 030209 endocrinology & metabolism Diabetes Complications 03 medical and health sciences 0302 clinical medicine Remission criteria medicine Humans In patient 030212 general & internal medicine Retrospective Studies business.industry Insulin Remission Induction Complete remission nutritional and metabolic diseases Type 2 Diabetes Mellitus Retrospective cohort study Middle Aged Surgery Obesity Morbid Treatment Outcome Diabetes Mellitus Type 2 Metabolic control analysis Female business |
| Zdroj: | Endocrinologia, diabetes y nutricion. 66(1) |
| ISSN: | 2530-0180 |
| Popis: | Objectives To assess remission of type 2 diabetes mellitus (T2DM) after bariatric surgery, to analyze potential conditioning factors, and to compare Spanish and American remission criteria. Material and methods A retrospective study of diabetic patients undergoing Roux-en-Y gastric bypass from 2009 to 2015. Data collected included age, sex, time since T2DM diagnosis, antidiabetic drugs, insulin (type and dose), weight and BMI, percent excess weight lost, HbA1c, blood glucose levels, and course of T2DM after surgery according to Spanish and American criteria, including a descriptive analysis and correlation between both. Results The study sample consisted of 106 patients. Outcomes one year after surgery was as follows (Spanish criteria): complete remission 65.9%, partial remission 5.5%, improvement 18.9%, no change 9.7% (at 5 years: 68.4, 5.3, 10.5, and 15.8%, respectively). Outcomes according to ADA criteria were as follows: complete remission 61.5%, partial remission 5.3%, and no remission 28.6% (after 5 years, complete remission 68.4%). There was a good correlation between both classifications (rho = 0.974; p Conclusions At our hospital, bariatric surgery is associated to a high remission rate of T2DM in patients with morbid obesity, with a good correlation between Spanish and American criteria. Age over 50 years old, long T2DM duration, poorer baseline metabolic control, and previous insulin treatment are markers of poorer response. |
| Databáze: | OpenAIRE |
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