RELEASE OF LH DURING TREATMENT WITH PURIFIED SHEEP FSH WITHOUT SIGNS OF ADEQUATE FOLLICULAR MATURATION IN WOMEN
| Autor: | C. S. Corker, Pamela C. B. MacKinnon, J. Gonzalez-Merlo, Pujol-Amat P |
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| Rok vydání: | 1972 |
| Předmět: |
endocrine system
Embryology medicine.medical_specialty Time Factors Follicle-stimulating hormone Endocrinology Ovarian Follicle Internal medicine Animals Humans Endocrine system Medicine Follicular maturation Amenorrhea Progesterone Sheep Estradiol business.industry Obstetrics and Gynecology Pituitary Hormone-Releasing Hormones Estrogens Cell Biology Luteinizing Hormone Reproductive Medicine Pregnanediol Female Follicle Stimulating Hormone FSH preparation medicine.symptom business Luteinizing hormone hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | Reproduction. 31:279-284 |
| ISSN: | 1741-7899 1470-1626 |
| DOI: | 10.1530/jrf.0.0310279 |
| Popis: | The release of luteinizing hormone (LH) during treatment with purified sheep follicle stimulating hormone (FSH) without signs of adequate follicular maturation in women is reported. 4 women with amenorrhoea for 2-7 years were treated with the FSH preparation. Plasma progesterone estradiol and LH concentrations were measured every 24 or 48 hours during 15-30 days of treatment. A LH peak was found in all 4 women even though in 3 of them there was no evidence of adequate follicu lar maturation as assessed by estradiol levels. These results indicate that an estradiol peak need not necessarily be the unique stimulus for LH release and the possibility that FSH in humans can stimulate LH release directly through a short loop feedback mechanism should not be disregarded. |
| Databáze: | OpenAIRE |
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