Monitoring the bulk milk antibody response to BVDV: the effects of vaccination and herd infection status
| Autor: | Joe Brownlie, M. P. Cranwell, Richard Booth |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Veterinary medicine
animal diseases Pilot Projects Antibodies Viral Virus Flaviviridae Medicine Animals Test interpretation Diarrhea Viruses Bovine Viral General Veterinary biology business.industry Pestivirus Vaccination Viral Vaccines General Medicine biology.organism_classification Virology Antibody response Milk Herd biology.protein Bovine Virus Diarrhea-Mucosal Disease Cattle Female Antibody business Sentinel Surveillance |
| Zdroj: | The Veterinary record. 172(17) |
| ISSN: | 2042-7670 |
| Popis: | Bovine Viral Diarrhoea Virus (BVDV) is a pestivirus in the flaviviridae family which affects cattle worldwide. Bulk milk (BM) antibody testing is frequently used as a relatively quick method of assessing herd BVDV exposure; however, an understanding of the effects of vaccination and historic infection is essential for test interpretation. This study investigated the trends exhibited by monthly BM antibody analysis in 14 herds split into three categories. Category 1 herds (vaccinating/no persistently infected (PI) animals) began the study with mid-positive BM antibody titres and experienced an estimated increase of 0.007 optical density (OD) units per month (equating to a rise of 0.35 OD units in 50 months). Category 2 herds (not vaccinating/no PI animals) began the study with mid-positive BM antibody titres and experienced an estimated decrease of 0.005 OD units per month with antibody levels in one category 2 herd taking 1290 days to decrease from mid-positive to negative. Category 3 herds (vaccinating/PI animals present) began the study with high BM antibody titres which plateaued within this range throughout the 50-month observation period. Vaccination was observed to cause transient increases in BM antibody in a number of herds in categories 1 and 3. |
| Databáze: | OpenAIRE |
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