Stress cardiomyopathy – a unique presentation of diabetic ketoacidosis
| Autor: | Shree Gopal Sharma, Santo Longo, John Pamula, Surya P. Bhatt, Sudip Nanda, Thompson H. Dale |
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| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
endocrine system diseases Diabetic ketoacidosis Cellular respiration business.industry Type i diabetes mellitus Clinical Biochemistry Cardiomyopathy High capacity General Medicine Middle Aged medicine.disease Diabetic Ketoacidosis carbohydrates (lipids) Endocrinology Echocardiography Stress Physiological Internal medicine medicine Humans Myocyte Female Cardiomyopathies business |
| Zdroj: | Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 46:257-260 |
| ISSN: | 1758-1001 0004-5632 |
| DOI: | 10.1258/acb.2009.008237 |
| Popis: | We have documented a unique instance of diabetic ketoacidosis (DKA)-induced stress-related cardiomyopathy (CMP) in a 46-yr-old Caucasian female with type I diabetes mellitus. In times of stress, tissues with high capacity for aerobic metabolism, like myocardium, can preferentially change their metabolic substrate to ketones. The myocyte has a decreased ability to metabolize glucose and free fatty acids in stress CMP. To the best of our knowledge this is the first report of stress CMP complicating DKA. A possible mechanism for the same is hypothesized. |
| Databáze: | OpenAIRE |
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