Liver transplantation in children: the experience of Queen Mary Hospital, Hong Kong
| Autor: | Sheung Tat Fan, N.S. Tsoi, GH Mya, Kwong-Leung Chan, Irene Oi-Lin Ng, Jwr Lo, Htut Saing, Kwok-Yung Yuen, Chung Mau Lo, J Wong, Jkf Chan, M.T. Chau, W.K. Tsoi, William I. Wei |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Male
Reoperation medicine.medical_specialty Microsurgery medicine.medical_treatment Anastomosis Liver transplantation Hepatitis Liver disease Hepatic Artery Postoperative Complications Biliary atresia Activities of Daily Living Living Donors Medicine Humans Child business.industry Anastomosis Surgical Body Weight Graft Survival Infant Thrombosis General Medicine Organ Size medicine.disease Surgery Liver Transplantation Transplantation Survival Rate Treatment Outcome Child Preschool Histocompatibility Pediatrics Perinatology and Child Health Etiology Hong Kong Female business Vascular Surgical Procedures Liver Failure Follow-Up Studies |
| Zdroj: | Journal of pediatric surgery. 32(1) |
| ISSN: | 0022-3468 |
| Popis: | Seven living-related liver transplants (LRLT) and two reduced-size liver transplants (RSLT) were performed on eight children who suffered from end-stage liver disease, having previously undergone one to three abdominal operations. Their ages at initial transplantation ranged from 8 months to 11 years (mean 35 months, median 12 months). Excluding the two older children aged 7 and 11 years, respectively, the rest of the children weighed 6 to 9.5 kg (mean 7.3 kg) at the time of the initial transplantation. Seven left lateral segments (S2 + 3) and two left lobes (S2 + 3 + 4) were used; of these the smallest graft had a graft-to-recipient body weight ratio of 0.9%. The volunteer living donors were four mothers, two fathers and one sister who were selected after medical and psychiatric evaluations, and their suitability was confirmed by hematological, biochemical, and radiological criteria. During a follow-up period of 3 to 30 months, all eight children are alive and well with normal liver function, one of them having undergone a retransplant LRLT because of hepatitis of undetermined etiology following a RSLT 1.5 years earlier. All seven donors had an uneventful postoperative course and were discharged on day 4 to 7 postoperatively. They have all resumed normal day-to-day activities. There were no complications in the donor group. A variety of complications occurred in the recipients, all of which were overcome. Operating microscope was used to perform all the arterial anastomoses using microvascular techniques. This method has proven to be a major factor in preventing arterial thrombosis even with the smallest of arterial anastomosis where a 1.5-mm diameter recipient artery was anastomosed to a 2.5-mm diameter donor hepatic artery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect