Partial Frontolateral Laryngectomy With Epiglottic Reconstruction for Management of Early-Stage Glottic Carcinoma
| Autor: | Antoine Giovanni, Michel Zanaret, Ping Yu, Régis Gras, Bruno Guelfucci |
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| Rok vydání: | 2001 |
| Předmět: |
Male
Glottis medicine.medical_specialty Epiglottis Time Factors medicine.medical_treatment Laryngectomy otorhinolaryngologic diseases medicine Carcinoma Humans Stage (cooking) Laryngeal Neoplasms Survival rate business.industry Retrospective cohort study Middle Aged Plastic Surgery Procedures medicine.disease Surgery Survival Rate Plastic surgery Treatment Outcome medicine.anatomical_structure Otorhinolaryngology Carcinoma Squamous Cell Female business |
| Zdroj: | The Laryngoscope. 111:663-668 |
| ISSN: | 0023-852X |
| DOI: | 10.1097/00005537-200104000-00020 |
| Popis: | Objectives The aim of this study was to demonstrate that partial frontolateral laryngectomy with epiglottic reconstruction (PFLER) is an effective therapeutic option for treatment of T1 and T2 glottic carcinoma. Study Design Retrospective study. Methods Between 1982 and 1997, we treated 127 cases of early glottic carcinoma with PFLER. Early glottic carcinoma was staged using the Union Internationale Contre le Cancer TNM classification as either T1N0M0 (62 cases) or T2N0M0 (65 cases). Selection criteria, depending on the limits of exeresis, must remain glottic carcinoma with less than 0.5 cm of anterior subglottic involvement, with no involvement of the supraglottic space or laryngeal side of the epiglottis, with involvement of only one arytenoid, and with good mobility of both arytenoids even if vocal cord mobility is decreased. Results Postoperative recovery was uneventful in all cases, and all patients but one were able to breath and eat normally. The failure involved a patient with a permanent gastrostomy. As with other partial laryngectomy techniques, the main drawback of PFLER was deterioration of voice quality. All patients presented hoarseness and weakness of the voice. Five-year survival rates calculated according to the Kaplan-Meier method were 91% (standard error, 5%) in the T1N0M0 group and 86% (standard error, 5%) in the T2N0M0 group. No recurrence was observed in the T1N0M0 group. Local control was successful in 92% in the T2N0M0 group after a median follow-up of 5 years. Conclusion These findings show that PFLER is an effective therapeutic option in selected cases of early T1N0M0 or T2N0M0 glottic carcinoma. |
| Databáze: | OpenAIRE |
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