| Autor: |
Atbin Djamshidian, Andrew J. Lees, Pedro Barbosa, Eileen M. Joyce, Sean S. O'Sullivan, Thomas T. Warner |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Mov Disord Clin Pract |
| ISSN: |
2330-1619 |
| DOI: |
10.1002/mdc3.13363 |
| Popis: |
BACKGROUND: Little is known about the cognitive and neuropsychiatric profile associated with punding and hobbyism in Parkinson's disease (PD). OBJECTIVE: To compare the clinical and neuropsychological features of PD patients with punding and hobbyism to PD controls. METHODS: The Questionnaire for Impulsive‐Compulsive Disorders in Parkinson's Disease‐Rating Scale (QUIP‐RS) was used as a screening tool, and a structured interview was used to diagnose punding/hobbyism. Clinical and neuropsychological assessment was conducted with validated questionnaires/scales. RESULTS: Twenty‐one patients with PD and punding (PD + pu) were compared to 26 with hobbyism (PD + h) and 25 PD controls. PD + pu patients showed higher levels of anxiety, non‐motor symptoms and motor symptoms, and lower Frontal Assessment Battery scores. The PD + h group exhibited similar levels of anxiety and motor fluctuations to the PD + pu group. CONCLUSION: PD + pu showed increased anxiety and frontal lobe dysfunction, similar to PD + h. Hobbyism could be a prodromal phase with increased risk of leading to punding. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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