A SUMOylation wave to anchor the genome
| Autor: | Adele L. Marston |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Protein sumoylation
0303 health sciences SUMO protein Mitosis Sumoylation Cell Biology Biology Genome Chromosomes Chromatin Cell biology Chromosome segregation 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Chromosome Segregation medicine Interphase Nuclear membrane 030217 neurology & neurosurgery 030304 developmental biology |
| Zdroj: | Marston, A L 2021, ' A sumoylation wave to anchor the genome ', Journal of Cell Biology, vol. 220, no. 12, e202110031 . https://doi.org/10.1083/jcb.202110031 |
| ISSN: | 1540-8140 0021-9525 |
| DOI: | 10.1083/jcb.202110031 |
| Popis: | Chromatin tethers to the nuclear envelope are lost during mitosis to facilitate chromosome segregation. How these connections are reestablished to ensure functional genome organization in interphase is unclear. Ptak et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202103036) identify a phosphorylation and SUMOylation-dependent cascade that links chromatin to the nuclear membrane during late mitosis. |
| Databáze: | OpenAIRE |
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