Circulating tumor cells in thyroid carcinoma - the prognostic role of this biomarker. Review of the literature
Autor: | Doina Piciu, Elena Barbus, Iulian Claudiu Bădulescu |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
Oncology
medicine.medical_specialty Pathology business.industry Incidence (epidemiology) Cancer General Medicine Disease Review circulating tumor cells medicine.disease thyroid carcinoma Metastasis Thyroid carcinoma Circulating tumor cell Internal medicine medicine Biomarker (medicine) prognosis business Thyroid cancer |
Zdroj: | Clujul Medical |
ISSN: | 2066-8872 1222-2119 |
Popis: | Thyroid cancer is a disease with a good prognosis and high survival rates, but having a marked growth of incidence all over the world in the last years. This fact requires special attention of researchers for understanding the behavior of this disease and to establish a correct therapy. Analysis of circulating tumor cells in patients with different malignancies is nowadays a new and exciting research tool, which can improve the diagnosis and prevent the metastatic disease. In the case of thyroid carcinoma there are few studies which explore these biomarkers and investigate the prognostic significance of circulating tumor cells. With this review we seek to emphasize the role of these cells to better understand the mechanisms of invasion or metastasis and to establish a new research base to treat aggressive forms of this type of cancer. Most of the included studies demonstrate the efficacy of these markers for diagnosis and follow up. |
Databáze: | OpenAIRE |
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