MEDIUM-GRADE ASTROCYTOMA IN A COUGAR (PUMA CONCOLOR)
Autor: | Jeffrey R. Abbott, Matti Kiupel, Lisa L. Farina, Angelique M. Leone, Claire Erlacher-Reid, Hirotaka Kondo, Joy Gary |
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Rok vydání: | 2012 |
Předmět: |
Male
Pathology medicine.medical_specialty Central nervous system Caudate nucleus Astrocytoma Gross examination Puma Mydriasis medicine Neuropil Animals General Veterinary Glial fibrillary acidic protein biology Brain Neoplasms General Medicine Anatomy medicine.disease biology.organism_classification medicine.anatomical_structure biology.protein Animal Science and Zoology medicine.symptom |
Zdroj: | Journal of Zoo and Wildlife Medicine. 43:956-960 |
ISSN: | 1937-2825 1042-7260 |
DOI: | 10.1638/2012-0106r1.1 |
Popis: | A 17-year-old, male castrated cougar (Puma concolor) was presented minimally responsive and severely depressed, with bilateral mydriasis and absent pupillary light response. On gross examination of the brain, there was a tan-to-gray, invasive mass with a central cavitation on the ventral aspect in the left cerebral hemisphere, rostral to the caudate nucleus. On histopathologic examination, the mass was composed of sheets of medium-sized, round-to-polygonal cells that were multifocally separated by islands of neuropil. Approximately 80% of the neoplastic cells showed strong cytoplasmic labeling for glial fibrillary acidic protein. These findings were consistent with a medium-grade astrocytoma. To the authors' knowledge, neoplastic disease of the central nervous system has not been previously reported in cougars. |
Databáze: | OpenAIRE |
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