MEDIUM-GRADE ASTROCYTOMA IN A COUGAR (PUMA CONCOLOR)

Autor: Jeffrey R. Abbott, Matti Kiupel, Lisa L. Farina, Angelique M. Leone, Claire Erlacher-Reid, Hirotaka Kondo, Joy Gary
Rok vydání: 2012
Předmět:
Zdroj: Journal of Zoo and Wildlife Medicine. 43:956-960
ISSN: 1937-2825
1042-7260
DOI: 10.1638/2012-0106r1.1
Popis: A 17-year-old, male castrated cougar (Puma concolor) was presented minimally responsive and severely depressed, with bilateral mydriasis and absent pupillary light response. On gross examination of the brain, there was a tan-to-gray, invasive mass with a central cavitation on the ventral aspect in the left cerebral hemisphere, rostral to the caudate nucleus. On histopathologic examination, the mass was composed of sheets of medium-sized, round-to-polygonal cells that were multifocally separated by islands of neuropil. Approximately 80% of the neoplastic cells showed strong cytoplasmic labeling for glial fibrillary acidic protein. These findings were consistent with a medium-grade astrocytoma. To the authors' knowledge, neoplastic disease of the central nervous system has not been previously reported in cougars.
Databáze: OpenAIRE