Uncommon Synchronous Association between Ovarian Carcinoma and Gastrointestinal Stromal Tumor: A Case Study and Literature Review

Autor: Favero, G., Pfiffer, T., Riedlinger, W., Schneider, A., Chiantera, Vito
Přispěvatelé: Favero, G., Pfiffer, T., Riedlinger, W., Chiantera, V., Schneider, A.
Rok vydání: 2013
Předmět:
Cancer Research
Paclitaxel
Gastrointestinal Stromal Tumors
Ovariectomy
Antigens
CD34
Carcinoma
Ovarian Epithelial
Cystectomy
Hysterectomy
Carboplatin
030218 nuclear medicine & medical imaging
Neoplasms
Multiple Primary
Salpingectomy
03 medical and health sciences
Pancreatectomy
0302 clinical medicine
Ovarian cancer
Synchronous occurrence
Stomach Neoplasm
Gastrectomy
Stomach Neoplasms
Antineoplastic Combined Chemotherapy Protocols
Gastrointestinal Stromal Tumor
Biomarkers
Tumor
Humans
Neoplasms
Glandular and Epithelial
Colectomy
Ovarian Neoplasms
Antineoplastic Combined Chemotherapy Protocol
Ovarian Neoplasm
General Medicine
Middle Aged
Immunohistochemistry
Proto-Oncogene Proteins c-kit
Treatment Outcome
Oncology
Chemotherapy
Adjuvant
CA-125 Antigen
030220 oncology & carcinogenesis
Splenectomy
Lymph Node Excision
Female
Human
Zdroj: Tumori Journal. 99:e70-e72
ISSN: 2038-2529
0300-8916
DOI: 10.1177/030089161309900232
Popis: Background The association of gastrointestinal stromal tumors (GIST) and other cancers is well known, but its synchronous occurrence with gynecological malignancies is very uncommon. Usually, the diagnosis is accidentally established. We describe a patient with GIST and concurrent ovarian cancer and discuss the clinical implications of this finding. Case report A 64-year-old woman with a prior diagnosis of ovarian cancer developed a second recurrence after having undergone two operations and adjuvant chemotherapy. While tumor debulking was performed, a small, nonsuspicious lesion was removed from the greater curvature of the stomach. Histology revealed a GIST. Conclusion The association of GIST and ovarian cancer is a rarity and its synchronicity may alter the oncological prognosis and therapy of the patient.
Databáze: OpenAIRE
Externí odkaz: