Factors involved in the rate of fall of thyroid stimulating hormone in treated hypothyroidism
| Autor: | Vipan Datta, Chris Cutts, Peter G F Swift, Nassos Thomas |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Male
endocrine system Pediatrics medicine.medical_specialty Time Factors endocrine system diseases Intellectual development medicine.medical_treatment Thyroid Gland Thyrotropin Neonatal Screening Hypothyroidism Thyroid-stimulating hormone Internal medicine Congenital Hypothyroidism medicine Humans Letters to the Editor Radionuclide Imaging Prospective cohort study Normal range Chemotherapy Analysis of Variance Chi-Square Distribution business.industry Thyroid disease Thyroid Infant Newborn Dosing regimen Infant Mean age Original Articles medicine.disease Congenital hypothyroidism Thyroxine medicine.anatomical_structure Endocrinology Thyroid hormones Paediatric endocrinology Pediatrics Perinatology and Child Health Female business Levothyroxine Sodium Follow-Up Studies |
| Zdroj: | Archives of Disease in Childhood. 79:198-198 |
| ISSN: | 1468-2044 0003-9888 |
| Popis: | Editor,—We would like to comment on the recommendations on the management of congenital hypothyroidism by Raza et al. 1 Although thyroxine dosage recommendations have been available for the treatment of congenital hypothyroidism for many years2 it has not been possible to answer the crucial question as to what concentrations of circulating thyroid hormones and degree of thyroid stimulating hormone (TSH) suppression are required to provide the optimal environment for maximising neurobehavioural and intellectual development. The working group on congenital hypothyroidism of the European Society for Paediatric Endocrinology has emphasised that it has not been possible to measure a dose–response relation, and it is coordinating a prospective study to assess the adequacy of treatment and outcome using two different dosage schedules for the first 24 months after birth. In the absence of randomised, prospective outcome studies, previous authors have recommended … |
| Databáze: | OpenAIRE |
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