Treatment of acute silicoproteinosis by whole-lung lavage

Autor: Michael J. Weyant, Marshall Stafford, Ferenc Puskas, Abigail R. Lara, Anthony Cappa, Nathaen Weitzel, James Ellis
Rok vydání: 2013
Předmět:
Zdroj: Seminars in cardiothoracic and vascular anesthesia. 17(2)
ISSN: 1940-5596
Popis: Acute silicoproteinosis is a rare disease that occurs following a heavy inhalational exposure to silica dusts. Clinically, it resembles pulmonary alveolar proteinosis (PAP); silica exposure is thought to be a cause of secondary PAP. We describe a patient with biopsy-confirmed acute silicoproteinosis whose course was complicated by acute hypoxemic respiratory failure requiring mechanical ventilation. Without clinical improvement despite antibiotic and steroid treatment, the patient was scheduled for whole-lung lavage under general anesthesia. Anesthetic challenges included double-lumen tube placement and single-lung ventilation in a hypoxic patient, facilitating lung lavage, and protecting the contralateral lung from catastrophic spillage.
Databáze: OpenAIRE