System architecture for a magnetically guided endovascular microcatheter

Autor: Vincent Malba, Anthony F. Bernhardt, Alastair J. Martin, R. Sincic, Daniel L Cooke, Steven W. Hetts, Erin J. Yee, Scott Goodfriend, Maythem Saeed, Jason Ni, Fabio Settecase, Neel Shah, Prasheel Lillaney, Curtis Caton, Aaron D. Losey, Lee Evans, Mark W. Wilson
Rok vydání: 2014
Předmět:
Scanner
Engineering
Catheters
Interventional magnetic resonance imaging
Swine
Image Processing
Biomedical Engineering
Solenoid
Image processing
Magnetic Resonance Imaging
Interventional
Imaging phantom
Article
Phantoms
Imaging
Analytical Chemistry
Magnetics
Computer-Assisted
Theoretical
Models
medicine
Image Processing
Computer-Assisted
Animals
Molecular Biology
Interventional MRI
Artifact (error)
medicine.diagnostic_test
Interventional
Endovascular
business.industry
Phantoms
Imaging
Animal
Endovascular Procedures
Angiography
Magnetic resonance imaging
Steady-state free precession imaging
Equipment Design
Materials Engineering
Models
Theoretical
Microcatheter
equipment and supplies
Magnetic Resonance Imaging
Magnetic Fields
Models
Animal
Biomedical Imaging
business
Artifacts
human activities
Biomedical engineering
Zdroj: Biomedical microdevices, vol 16, iss 1
Popis: Magnetic resonance imaging (MRI) guided minimally invasive interventions are an emerging technology. We developed a microcatheter that utilizes micro-electromagnets manufactured on the distal tip, in combination with the magnetic field of a MRI scanner, to perform microcatheter steering during endovascular surgery. The aim of this study was to evaluate a user control system for operating, steering and monitoring this magnetically guided microcatheter. The magnetically-assisted remote control (MARC) microcatheter was magnetically steered within a phantom in the bore of a 1.5 Tesla MRI scanner. Controls mounted in an interventional MRI suite, along with a graphical user interface at the MRI console, were developed with communication enabled via MRI compatible hardware modules. Microcatheter tip deflection measurements were performed by evaluating MRI steady-state free precession (SSFP) images and compared to models derived from magnetic moment interactions and composite beam mechanics. The magnitude and direction of microcatheter deflections were controlled with user hand, foot, and software controls. Data from two different techniques for measuring the microcatheter tip location within a 1.5 Tesla MRI scanner showed correlation of magnetic deflections to our model (R2: 0.88) with a region of linear response (R2: 0.98). Image processing tools were successful in autolocating the in vivo microcatheter tip within MRI SSFP images. Our system showed good correlation to response curves and introduced low amounts of MRI noise artifact. The center of the artifact created by the energized microcatheter solenoid was a reliable marker for determining the degree of microcatheter deflection and auto-locating the in vivo microcatheter tip.
Databáze: OpenAIRE
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