Neuropsychological development in adolescents: Longitudinal associations with white matter microstructure
| Autor: | Ines Mürner-Lavanchy, Susanne Schell, Ayaka Ando, Julian Koenig, Romuald Brunner, Michael Kaess, Franz Resch, Romy Henze |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Cognitive Neuroscience 610 Medicine & health Audiology Neuropsychological Tests Development 050105 experimental psychology White matter 03 medical and health sciences 0302 clinical medicine Cognition Fractional anisotropy medicine Cognitive development Cingulum (brain) Humans 0501 psychology and cognitive sciences Longitudinal Studies 100 Philosophie und Psychologie::150 Psychologie::150 Psychologie Child Original Research 05 social sciences Superior longitudinal fasciculus lcsh:QP351-495 Neuropsychology Brain White Matter medicine.anatomical_structure Diffusion tensor imaging lcsh:Neurophysiology and neuropsychology White matter microstructure Longitudinal Female Psychology 030217 neurology & neurosurgery Diffusion MRI |
| Zdroj: | Developmental Cognitive Neuroscience, Vol 45, Iss, Pp 100812-(2020) Developmental Cognitive Neuroscience Mürner-Lavanchy, Ines M.; Koenig, Julian; Ando, Ayaka; Henze, Romy; Schell, Susanne; Resch, Franz; Brunner, Romuald; Kaess, Michael (2020). Neuropsychological development in adolescents: Longitudinal associations with white matter microstructure. Developmental Cognitive Neuroscience, 45, p. 100812. Elsevier 10.1016/j.dcn.2020.100812 |
| DOI: | 10.7892/boris.145094 |
| Popis: | Important neuropsychological changes during adolescence coincide with the maturation of white matter microstructure. Few studies have investigated the association between neuropsychological development and white matter maturation longitudinally. We aimed to characterize developmental trajectories of inhibition, planning, emotion recognition and risk-taking and examine whether white matter microstructural characteristics were associated with neuropsychological development above and beyond age. In an accelerated longitudinal cohort design, n 1/4 112 healthy adolescents between ages 9 and 16 underwent cognitive assessment and diffusion MRI over three years. Fractional anisotropy (FA) and mean diffusivity (MD) were extracted for major white matter pathways using an automatic probabilistic reconstruction technique and mixed models were used for statistical analyses. Inhibition, planning and emotion recognition performance improved linearly across adolescence. Risk-taking developed in a quadratic fashion, with stable performance between 9 and 12 and an increase between ages 12 and 16. Including cingulum and superior longitudinal fasciculus FA slightly improved model fit for emotion recognition across age. We found no evidence that FA or MD were related to inhibition, planning or risk-taking across age. Our results challenge the additional value of white matter microstructure to explain neuropsychological development in healthy adolescents, but more longitudinal research with large datasets is needed to identify the potential role of white matter microstructure in cognitive development. |
| Databáze: | OpenAIRE |
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