Mechanism research on combination of decoction for reinforcing lung Qi and argon helium lancet in treatment of non-small cell lung cancer
| Autor: | Xiao Zhang, Shao-dan Li, Yue-yong Xiao, Jie Li, Yu Feng, Yin Zhang, Ke Cao |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Lung Neoplasms genetic structures Molecular mechanisms of pharmacological action Qi Decoction Gastroenterology Flow cytometry Argon helium lancet Internal medicine medicine Humans Lung cancer Lung Aged Medicine(all) Traditional medicine medicine.diagnostic_test Tumor Necrosis Factor-alpha business.industry General Medicine Middle Aged respiratory system Carcinoma non-small-cell lung medicine.disease Peripheral blood respiratory tract diseases medicine.anatomical_structure Lasers Gas Interleukin-2 Reinforcing lung Female Tumor necrosis factor alpha Non small cell business After treatment |
| Zdroj: | Journal of Traditional Chinese Medicine. 33(3):307-311 |
| ISSN: | 0254-6272 |
| DOI: | 10.1016/s0254-6272(13)60170-3 |
| Popis: | Objective To observe the effect of decoction for reinforcing lung Qi on T-lymphocytic function, interleukin-2 (IL-2) and tumor necrosis factor-α (TNF-α) in peripheral blood of patients with non-small cell lung cancer after operation with argon helium lancet in order to explore its mechanism. Methods A total of 76 patients suffering from non-small cell lung cancer without surgical indication were randomly divided into a treatment group treated with decoction for reinforcing lung Qi and argon helium lancet and a control group treated with argon helium lancet only to observe lymphocytic proliferation, detect the percentage of positive cells in the T-lymphocyte CD 28 with flow cytometry and detect the expression of IL-2 and TNF-α in peripheral blood with enzyme linked immunosorbent assay. Results Proliferation of T-lymphocytes and expression of CD 28 , IL-2 and TNF-α in peripheral blood after treatment in the treatment group were more obviously strengthened than those before treatment and those in the control group (all P Conclusion The mechanism of using decoction for reinforcing lung Qi and argon helium lancet to treat lung cancer may be realized through promoting T-lymphocytic proliferation, up-regulating expression of CD 28 , IL-2 and TNF-α, and activating T-cells. |
| Databáze: | OpenAIRE |
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