Prognostic Value of Coronary Flow Reserve Obtained on Dobutamine Stress Echocardiography and its Correlation with Target Heart Rate
| Autor: | José Nogueira Paes Júnior, Ana Gardenia Liberato Ponte Farias, Isadora Sucupira Machado, José Sebastião de Abreu, Tereza Cristina Pinheiro Diógenes, Fernando José Villar Nogueira Paes, Isabelle Oliveira Parahyba, Marcia Maria Carneiro, Marília Esther Benevides de Abreu, Thaís de Brito Rocha, Eduardo Arrais Rocha |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
lcsh:Diseases of the circulatory (Cardiovascular) system
medicine.medical_specialty Dobutamine stress echocardiography Prognóstico Fractional flow reserve Ecocardiografia sob Estresse 030204 cardiovascular system & hematology Target heart rate 03 medical and health sciences 0302 clinical medicine Heart Rate Internal medicine medicine 030212 general & internal medicine business.industry Follow up studies Coronary flow reserve Articles Prognosis Fractional Flow Reserve Myocardial Reserva Fracionada de Fluxo Cardíaco lcsh:RC666-701 Cardiology Frequência Cardíaca Cardiology and Cardiovascular Medicine business Echocardiography Stress |
| Zdroj: | Arquivos Brasileiros de Cardiologia v.108 n.5 2017 Arquivos Brasileiros de Cardiologia Sociedade Brasileira de Cardiologia (SBC) instacron:SBC Arquivos Brasileiros de Cardiologia, Vol 108, Iss 5, Pp 417-426 |
| Popis: | Background: Normal coronary flow velocity reserve (CFVR) (≥ 2) obtained in the left anterior descending coronary artery (LAD) from transthoracic echocardiography is associated with a good prognosis, but there is no study correlating CFVR with submaximal target heart rate (HR). Objective: To evaluate the prognostic value of CFVR obtained in the LAD of patients with preserved (>50%) left ventricular ejection fraction (LVEF) who completed a dobutamine stress echocardiography (DSE), considering target HR. Methods: Prospective study of patients with preserved LVEF and CFVR obtained in the LAD who completed DSE. In Group I (GI = 31), normal CFVR was obtained before achieving target HR, and, in Group II (GII = 28), after that. Group III (G III=24) reached target HR, but CFVR was abnormal. Death, acute coronary insufficiency, coronary intervention, coronary angiography without further intervention, and hospitalization were considered events. Results: In 28 ± 4 months, there were 18 (21.6%) events: 6% (2/31) in GI, 18% (5/28) in GII, and 46% (11/24) in GIII. There were 4 (4.8%) deaths, 6 (7.2%) coronary interventions and 8 (9.6%) coronary angiographies without further intervention. In event-free survival by regression analysis, GIII had more events than GI (p < 0.001) and GII (p < 0.045), with no difference between GI and GII (p = 0.160). After adjustment, the only difference was between GIII and GI (p = 0.012). Conclusion: In patients with preserved LVEF and who completed their DSE, normal CFVR obtained before achieving target HR was associated with better prognosis. |
| Databáze: | OpenAIRE |
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