Association between non-alcoholic hepatic steatosis and hyper reactive blood pressure response on the exercise treadmill test
| Autor: | Khurram Nasir, Nea Miwa Kashiwagi, Michael J. Blaha, Raul D. Santos, Rogério Ruscitto do Prado, Jose A.M. Carvalho, Roger S. Blumenthal, Márcio Sommer Bittencourt, Romeu Sergio Meneghelo, Antonio G. Laurinavicius, Fernando Costa Nary, Raquel D. Conceição |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Waist Blood Pressure 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Non-alcoholic Fatty Liver Disease Internal medicine medicine Humans Prospective Studies Treadmill Ultrasonography medicine.diagnostic_test business.industry Fatty liver Blood Pressure Determination General Medicine Odds ratio Middle Aged medicine.disease Original Papers Blood pressure Endocrinology Logistic Models Abdominal ultrasonography Hypertension Multivariate Analysis Cardiology Exercise Test 030211 gastroenterology & hepatology Female Steatosis business Body mass index human activities Brazil |
| Popis: | Aims: Non-alcoholic hepatic steatosis (HS) is associated with hypertension and increased cardiovascular risk. While Blood pressure hyper-reactive response (HRR) during peak exercise indicates an increased risk of incident hypertension and increased cardiovascular risk, no data on the association of non-alcoholic HS and HRR exists. In this study, we have evaluated the association of HS with HRR. Methods: We included 13 410 consecutive individuals with a mean age: 42.4 ± 8.9 years, 3561 (26.6%) female with normal resting blood pressure and without a previous diagnosis of hypertension, who underwent symptom limited exercise treadmill test, abdominal ultrasonography and clinical and laboratory evaluation. HS was detected by abdominal ultrasonography. HRR was defined by a peak exercise systolic blood pressure >220 mmHg and/or elevation of 15 mmHg or more in diastolic blood pressure from rest to peak exercise. Results: The prevalence of HS was 29.5% ( n = 3956). Overall, 4.6% ( n = 619) of the study population presented a HRR. Subjects with HS had a higher prevalence of HRR (8.1 vs. 3.1%, odds ratio 2.8, 95% CI 2.4—3.3, P |
| Databáze: | OpenAIRE |
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