Vascular Health in Kawasaki Disease
Autor: | Elif Seda Selamet Tierney, Stephen R. O'Neill, Michael R. Jaff, Shari Trevey, Kimberly Gauvreau, David Fulton, Jane W. Newburger, Dana Gal, Annette L. Baker, Steven D. Colan, Sarah D. de Ferranti |
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Rok vydání: | 2013 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent Population Mucocutaneous Lymph Node Syndrome Young Adult Right Common Carotid Artery endothelial function Internal medicine medicine.artery medicine Humans Common carotid artery education Child Ultrasonography Coronary artery aneurysm education.field_of_study biology business.industry C-reactive protein medicine.disease Coronary Vessels coronary artery aneurysm vascular health Surgery medicine.anatomical_structure Intima-media thickness Case-Control Studies Kawasaki biology.protein Cardiology Kawasaki disease Female atherosclerosis business Cardiology and Cardiovascular Medicine Artery Boston |
Zdroj: | Journal of the American College of Cardiology. 62(12):1114-1121 |
ISSN: | 0735-1097 |
DOI: | 10.1016/j.jacc.2013.04.090 |
Popis: | ObjectivesThe objective of our study was to compare the indices of vascular health in Kawasaki disease (KD) patients to those of control subjects.BackgroundThe literature on peripheral vascular health after KD is conflicting.MethodsSubjects were patients 11 to 29 years of age with the onset of KD >12 months before the study visit (n = 203) and healthy control subjects (n = 50). We measured endothelial function (using the Endothelial Pulse Amplitude Testing index), intima-media thickness (IMT) of the right common carotid artery (RCCA) and the left common carotid artery (LCCA), and fasting lipid profile and C-reactive protein (CRP). KD patients were classified according to their worst-ever coronary artery (CA) status: group I, always normal CAs (n = 136, 67%); group II, CA z-scores ≥2 but |
Databáze: | OpenAIRE |
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