Gender-related presentation, surgical treatment, outcome and failure to rescue after surgery for type A aortic dissection: results from a multicentre registry
| Autor: | Alessandra Francica, Igor Vendramin, Stefano Salizzoni, Augusto D’Onofrio, Giuseppe Gatti, Mauro Rinaldi, Gino Gerosa, Aniello Pappalardo, Ugolino Livi, Giuseppe Faggian, Francesco Onorati |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male Thoracic Aorta Thoracic coma failure to rescue Blood Vessel Prosthesis Implantation Risk Factors gender Humans Registries Aorta Retrospective Studies acute aortic dissection neurological dysfunction Aortic Aneurysm Thoracic acute kidney injury General Medicine Middle Aged Aneurysm Aortic Aneurysm Aortic Dissection Coma Female Treatment Outcome Aneurysm Dissecting Surgery Cardiology and Cardiovascular Medicine Dissecting |
| Popis: | OBJECTIVES Reports on gender-related differences in perioperative characteristics and the outcome after surgery for type A acute aortic dissection are contradictory. METHODS Perioperative characteristics, outcome and overall or itemized failure-to-rescue rates were collected retrospectively and dichotomized by gender in patients operated on at 5 referral institutions. A propensity score matched analysis was performed to compared males and females with similar preoperative risk profiles. Multivariable analysis assessed gender-related predictors of 30-day mortality. RESULTS A total of 1271 patients were collected. Females (on average, 63 years old) developed type A acute aortic dissection, with differences in clinical presentation (number of intimal tears, thoracic pain at the onset of symptoms). Female-reported characteristics included lower frozen elephant trunk and elephant trunk procedures, higher femoral perfusion, retrograde cerebral perfusion and retrograde cardiopulmonary bypass restart after deep hypothermic circulatory arrest (P CONCLUSIONS Different surgical techniques and operative strategies were used on the 2 genders, with a lower complexity in females. However, there were no differences in hospital outcome between genders, except for the higher incidence of coma in female patients. |
| Databáze: | OpenAIRE |
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