Evaluation of HBV-Like circulation in wild and farm animals from Brazil and Uruguay
| Autor: | João Bosco Vilela Campos, Fernanda Cavalcanti de Azevedo, Livia Melo Villar, Fernando Queiroz de Almeida, Frederico Gemesio Lemos, Heitor Miraglia Herrera, Fabiana Lopes Rocha, Martha Lima Brandão, Luana Avila Giorgia Dimache, Ubiratan Piovezan, Yasmine Rangel Vieira, Flávia F Oliveira, Alexandro Guterres, Vanessa Salete de Paula, Moyra Machado Portilho, Juan Arbiza, Aiesca Oliveira Pellegrin, Igor Alexandre Hany Fuzeta Schabib Péres, Santiago Mirazo, N. P. Zimmermann, José Luis Passos Cordeiro, Gabriel Carvalho de Macedo, Marcelo Alves Pinto, Debora Regina Lopes dos Santos |
|---|---|
| Přispěvatelé: | YASMINE R. VIEIRA, Fundação Oswaldo Cruz, Rio de Janeiro., MOYRA M. PORTILHO, Fundação Oswaldo Cruz, Rio de Janeiro, FLÁVIA F. OLIVEIRA, Fundação Oswaldo Cruz, Rio de Janeiro, ALEXANDRO GUTERRES, Fundação Oswaldo Cruz, Rio de Janeiro, DÉBORA REGINA L DOS SANTOS, Universidade Federal Rural do Rio de Janeiro, LÍVIA M. VILLAR, Fundação Oswaldo Cruz, Rio de Janeiro, SANTIAGO MIRAZO, Universidad de la República, Montevideo, JUAN ARBIZA, Universidad de la República, Montevideo, LUANA A. G. DIMACHE, Universidade Federal Rural do Rio de Janeiro, FERNANDO Q. ALMEIDA, Universidade Federal Rural do Rio de Janeiro, MARTHA L. BRANDÃO, Fundação Oswaldo Cruz, JOSÉ LUÍS P. CORDEIRO, Fundação Oswaldo Cruz, FABIANA L. ROCHA, Universidade Federal da Paraíba, FERNANDA C. AZEVEDO, Programa de Conservação Mamíferos do Cerrado (PCMC), Cumari, GO, FREDERICO G. LEMOS, Programa de Conservação Mamíferos do Cerrado (PCMC), Cumari, GO, JOÃO BOSCO V. CAMPOS, Universidade Católica Dom Bosco, Campo Grande, MS, GABRIEL C. MACEDO, Universidade Católica Dom Bosco, Campo Grande, MS, HEITOR M. HERRERA, Universidade Católica Dom Bosco, Campo Grande, MS, IGOR ALEXANDRE HANY FUZETA S PERES, CPAP, NAMOR P. ZIMMERMANN, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, UBIRATAN PIOVEZAN, CPATC, AIESCA OLIVEIRA PELLEGRIN, CPAP, VANESSA S. DE PAULA, Fundação Oswaldo Cruz, RJ, MARCELO A. PINTO, Fundação Oswaldo Cruz, Rio de Janeiro., Vieira Y.R., Portilho M.M., Oliveira F.F., Guterres A., Santos D.R.L., Villar L.M., Mirazo Santiago, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Química Biológica., Arbiza Juan, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Biología, Dimache L.A.G., Almeida F.Q., Brandão M.L., Cordeiro J.L.P., Rocha F.L., Azevedo F.C., Lemos F.G., Campos J.B.V., Macedo G.C., Herrera H.M., Péres I.A.S., Zimmermann N.P., Piovezan U., Pellegrin A.O., Paula V.S., Pinto M.A. |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Disease impact
HBsAg Health Toxicology and Mutagenesis lcsh:Medicine medicine.disease_cause Polymerase Chain Reaction law.invention Serology law reverse zoonoses Polymerase chain reaction 0303 health sciences Transmission (medicine) Hepatitis B Hepadnavirus Animal diseases Real-time polymerase chain reaction Animals Domestic Viruses Brazil Hepatitis B virus Doença Animal Animals Wild Biology Article Virus Hepatitis B Antigens 03 medical and health sciences medicine Animal infectious diseases Animals Hepatitis B Antibodies hepadnavirus 030304 developmental biology 030306 microbiology animal infectious diseases lcsh:R Public Health Environmental and Occupational Health Vírus Virology Reverse zoonoses DNA Viral Uruguay disease impact Hepatite real-time PCR Biomarkers Real-time PCR |
| Zdroj: | Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice) Empresa Brasileira de Pesquisa Agropecuária (Embrapa) instacron:EMBRAPA International Journal of Environmental Research and Public Health Volume 16 Issue 15 International Journal of Environmental Research and Public Health, Vol 16, Iss 15, p 2679 (2019) COLIBRI Universidad de la República instacron:Universidad de la República |
| Popis: | The origin of the hepatitis B virus is a subject of wide deliberation among researchers. As a result, increasing academic interest has focused on the spread of the virus in different animal species. However, the sources of viral infection for many of these animals are unknown since transmission may occur from animal to animal, human to human, animal to human, and human to animal. The aim of this study was to evaluate hepadnavirus circulation in wild and farm animals (including animals raised under wild or free conditions) from different sites in Brazil and Uruguay using serological and molecular tools. A total of 487 domestic wild and farm animals were screened for hepatitis B virus (HBV) serological markers and tested via quantitative and qualitative polymerase chain reaction (PCR) to detect viral DNA. We report evidence of HBsAg (surface antigen of HBV) and total anti-HBc (HBV core antigen) markers as well as low-copy hepadnavirus DNA among domestic and wild animals. According to our results, which were confirmed by partial genome sequencing, as the proximity between humans and animals increases, the potential for pathogen dispersal also increases. A wider knowledge and understanding of reverse zoonoses should be sought for an effective One Health response. Made available in DSpace on 2020-02-13T18:16:05Z (GMT). No. of bitstreams: 1 EvaluationofHBVLike2019.pdf: 1254406 bytes, checksum: 6d7eb67e61fa36a7e3f57a679fdcc21f (MD5) Previous issue date: 2019 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|