Lower limb arterial intervention or autologous platelet-rich gel treatment of diabetic lower extremity arterial disease patients with foot ulcers

Autor: Weiling Leng, Yanling Zheng, Ziwen Liang, Xiaotian Lei, Liu Chen, Qinan Wu, Danlan Pu, Bing Chen
Rok vydání: 2019
Předmět:
Zdroj: Annals of Translational Medicine. 7:485-485
ISSN: 2305-5847
2305-5839
DOI: 10.21037/atm.2019.07.87
Popis: BACKGROUND: To investigate whether lower limb vascular intervention or autologous platelet-rich gel (APG) treatment would benefit diabetic lower extremity arterial disease (LEAD) patients with foot ulcers. METHODS: A total of 82 diabetic LEAD patients with foot ulcers were recruited and divided into three groups: group A (30 patients received basal treatment), group B (21 patients received basal and APG treatment), and group C (31 patients received basal and lower limb vascular intervention treatment). All patients underwent routine follow-up visits for 6 months. The baseline characteristics and parameters were examined. After treatment, changes in all parameters from baseline were recorded. The differences between groups and the relationship among each parameter were determined. RESULTS: There were no differences in the ankle brachial index (ABI) or major amputation between groups A and B (P>0.05). Compared with groups A and B, the ABI and major amputation rate of group C were improved (P0.05). Compared with groups A and C, TcPO(2), the heal rate and minor amputation of group B were improved (P
Databáze: OpenAIRE