Lower limb arterial intervention or autologous platelet-rich gel treatment of diabetic lower extremity arterial disease patients with foot ulcers
Autor: | Weiling Leng, Yanling Zheng, Ziwen Liang, Xiaotian Lei, Liu Chen, Qinan Wu, Danlan Pu, Bing Chen |
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Rok vydání: | 2019 |
Předmět: |
business.industry
medicine.medical_treatment Incidence (epidemiology) 030209 endocrinology & metabolism General Medicine 030204 cardiovascular system & hematology Group B Microcirculation 03 medical and health sciences Basal (phylogenetics) chemistry.chemical_compound 0302 clinical medicine medicine.anatomical_structure chemistry Amputation Anesthesia Angioplasty medicine Original Article TCPO Ankle business |
Zdroj: | Annals of Translational Medicine. 7:485-485 |
ISSN: | 2305-5847 2305-5839 |
DOI: | 10.21037/atm.2019.07.87 |
Popis: | BACKGROUND: To investigate whether lower limb vascular intervention or autologous platelet-rich gel (APG) treatment would benefit diabetic lower extremity arterial disease (LEAD) patients with foot ulcers. METHODS: A total of 82 diabetic LEAD patients with foot ulcers were recruited and divided into three groups: group A (30 patients received basal treatment), group B (21 patients received basal and APG treatment), and group C (31 patients received basal and lower limb vascular intervention treatment). All patients underwent routine follow-up visits for 6 months. The baseline characteristics and parameters were examined. After treatment, changes in all parameters from baseline were recorded. The differences between groups and the relationship among each parameter were determined. RESULTS: There were no differences in the ankle brachial index (ABI) or major amputation between groups A and B (P>0.05). Compared with groups A and B, the ABI and major amputation rate of group C were improved (P0.05). Compared with groups A and C, TcPO(2), the heal rate and minor amputation of group B were improved (P |
Databáze: | OpenAIRE |
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