Coeliac Disease With Rheumatoid Arthritis: An Unusual Association

Autor:	Bhupen Barman, Hage Nobin, K G Lynrah, Obang Perme, Synrang Batngen Warjri, Tony Ete, Taso Beyong
Rok vydání:	2015
Předmět:	Autoimmune disease Intestinal permeability Coeliac disease business.industry nutritional and metabolic diseases Case Report medicine.disease medicine.disease_cause digestive system diseases Autoimmunity Immune system Antigen Rheumatoid arthritis Immunology medicine Genetic predisposition business
Zdroj:	Gastroenterology Research
ISSN:	1918-2813 1918-2805
DOI:	10.14740/gr641w
Popis:	Coeliac disease has a significant association with many autoimmune disorders. It shares many common genetic and immunological features with other autoimmune diseases. Gluten, a gut-derived antigen, is the driver of the autoimmunity seen in coeliac disease. The altered intestinal permeability found in coeliac patients, coupled with a genetic predisposition and altered immunological response, may result in a systemic immune response that is directed against sites other than the gut. Gut-derived antigens may have a role in the pathogenesis of other autoimmune disorders including rheumatoid arthritis. Here we report a case of adult coeliac disease associated with rheumatoid arthritis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07843eb781691b2755b091a603224cf https://doi.org/10.14740/gr641w Zobrazit plný text záznamu