The Ketogenic Diet: Additional Information From a Crossover Study
| Autor: | John M. Freeman |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
genetic structures medicine.medical_treatment Treatment outcome Carbohydrate metabolism Placebo Epilepsy Saccharin Internal medicine medicine Humans Single-Blind Method Child Evoked Potentials Caloric Restriction Cross-Over Studies business.industry Brain Electroencephalography Ketones medicine.disease Crossover study Glucose Treatment Outcome Endocrinology Sweetening Agents Pediatrics Perinatology and Child Health Neurology (clinical) Ketosis Diet Ketogenic Food Deprivation business Ketogenic diet |
| Zdroj: | Journal of Child Neurology. 24:509-512 |
| ISSN: | 1708-8283 0883-0738 |
| DOI: | 10.1177/0883073808324776 |
| Popis: | The purpose of this blinded, crossover study of the ketogenic diet in children with the Lennox-Gastaut syndrome was to confirm, by the addition of 60 g of glucose per day to negate the ketosis, that the effectiveness of the ketogenic diet was neither the result of a placebo effect nor due to parental expectations and commitment. We found that the additional glucose did not significantly alter the frequency of electroencephalography-assessed events, but did decrease the frequency of parent-reported ``drop'' seizures (P = .07). Fasting had substantial effects on both seizures and electroencephalography-assessed events. The diet remained effective in decreasing seizures of the Lennox-Gastaut syndrome at 12 days, 6 months, and 12 months. In conclusion, the ketogenic diet is effective in decreasing the drop seizures of the Lennox-Gastaut syndrome. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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