Sub-millimeter fMRI at 1.5 Tesla: Correlation of high resolution with low resolution measurements

Autor: F.G.C. Hoogenraad, Jürgen R. Reichenbach, Serge A.R.B. Rombouts, Mark B. M. Hofman, E. Mark Haacke, Petra J. W. Pouwels
Přispěvatelé: ACS - Atherosclerosis & ischemic syndromes, ACS - Heart failure & arrhythmias, Amsterdam Neuroscience - Brain Imaging, NCA - Brain imaging technology, Physics and medical technology
Jazyk: angličtina
Rok vydání: 1999
Předmět:
Zdroj: Journal of Magnetic Resonance Imaging, 9(3), 475-482
ISSN: 1053-1807
Popis: Functional magnetic resonance imaging of the visual cortex with an in- plane resolution of 0.4 x 0.4 mm2 was performed using a simple visual stimulus resulting in clear maps of activation. A collapsing filter was used to compare these high-resolution images with low-resolution images collected during the same session. A good correspondence between the high- and low- resolution functional maps was found with respect to the center of localization of activation. However, only 20% of the size of activated areas in the low-resolution experiment was observed at high resolution. Which was partly caused by the difference in signal-to-noise ratio. The high-resolution images produce signal changes much higher than the low-resolution images due to reduced partial volume effects. Additionally, the high-resolution functional maps were compared with detailed anatomical and venous information. The activated areas were predominantly observed at venous vessels within the sulci with a diameter on the order of the pixel size.
Databáze: OpenAIRE