Data Rich, Information Poor: Can We Use Electronic Health Records to Create a Learning Healthcare System for Pharmaceuticals?
| Autor: | Valérie Paris, Martin Wenzl, Brigitte Bloechl-Daum, Guido Rasi, Paul A. Kyrle, Karl Broich, Thomas Senderovitz, Hans-Georg Eichler, Luke Slawomirski, Rui Santos Ivo, Jillian Oderkirk, Ad Schuurman |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Evidence-based practice
Knowledge management Technology Assessment Biomedical Biomedical Drug Industry International Cooperation Decision Making MEDLINE Reviews Health records Technology assessment 030226 pharmacology & pharmacy Settore MED/07 03 medical and health sciences 0302 clinical medicine Drug Development Technology Assessment Electronic Health Records Humans Pharmacology (medical) Healthcare data Reimbursement Randomized Controlled Trials as Topic Pharmacology business.industry Health technology Delivery of Health Care Learning Health System State of the Art 030220 oncology & carcinogenesis Business Healthcare system |
| Zdroj: | Clinical Pharmacology and Therapeutics |
| ISSN: | 1532-6535 0009-9236 |
| Popis: | Judicious use of real-world data (RWD) is expected to make all steps in the development and use of pharmaceuticals more effective and efficient, including research and development, regulatory decision making, health technology assessment, pricing, and reimbursement decisions and treatment. A "learning healthcare system" based on electronic health records and other routinely collected data will be required to harness the full potential of RWD to complement evidence based on randomized controlled trials. We describe and illustrate with examples the growing demand for a learning healthcare system; we contrast the exigencies of an efficient pharmaceutical ecosystem in the future with current deficiencies highlighted in recently published Organisation for Economic Co-operation and Development (OECD) reports; and we reflect on the steps necessary to enable the transition from healthcare data to actionable information. A coordinated effort from all stakeholders and international cooperation will be required to increase the speed of implementation of the learning healthcare system, to everybody's benefit. |
| Databáze: | OpenAIRE |
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