Consecutive borylcupration/C-C coupling of γ-alkenyl aldehydes towards diastereoselective 2-(borylmethyl)cycloalkanols
| Autor: | Ricardo J. Maza, Elena Fernández, Jordi Royes, Jorge J. Carbó |
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| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_classification
Double bond Chemistry Stereochemistry Metals and Alloys Regioselectivity chemistry.chemical_element General Chemistry Copper Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials C c coupling Intramolecular force Materials Chemistry Ceramics and Composites Computational analysis |
| Zdroj: | Chemical communications (Cambridge, England). 56(44) |
| ISSN: | 1364-548X |
| Popis: | Copper(i) catalyzes the borylative cyclization of γ-alkenyl aldehydes through chemo- and regioselective addition of Cu-B to C[double bond, length as m-dash]C and concomitant intramolecular 1,2-addition of Cu-C on C[double bond, length as m-dash]O. The products are formed in an exclusive diastereoselective manner and computational analysis identifies the key points for the observed chemo- and diastereoselectivity. |
| Databáze: | OpenAIRE |
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